Neuropeptide tyrosine (NPY) immunoreactivity in norepinephrine-containing cells and nerves of the mammalian adrenal gland.
Neuropeptide tyrosine (NPY) immunoreactivity in norepinephrine-containing cells and nerves of the mammalian adrenal gland.
复制标题
哺乳动物肾上腺的去甲肾上腺素细胞和神经中的神经肽酪氨酸（NPY）免疫反应性。
作者：
I. Varndell;J. Polak;J. Allen;G. Terenghi;S. Bloom
免疫细胞化学在光镜和电镜下的应用表明，神经肽酪氨酸（NPY）免疫反应物质定位于肾上腺髓质中含有去甲肾上腺素的内分泌细胞，以及穿透肾上腺皮质的几种哺乳动物（包括马、猫、大鼠、豚鼠和小鼠）的静脉曲张神经纤维。相关电镜免疫染色显示，脑啡肽和NPY的免疫反应共定位于同一种含去甲肾上腺素的分泌颗粒。从小鼠肾上腺中提取了高浓度的NPY （1243.7 +/- 122.8 pmol NPY/g湿组织，平均+/- SE）。色谱分析表明，提取的物质符合纯天然NPY。
The application of immunocytochemistry at both light and electron microscopic levels has revealed neuropeptide tyrosine (NPY)-immunoreactive material to be localized to norepinephrine-containing endocrine cells in the adrenal medulla and also to varicose nerve fibers penetrating the adrenal cortex of several mammalian species, including horse, cat, rat, guinea pig and mouse. Correlative electron microscopic immunostaining has revealed that enkephalin and NPY immunoreactivities are co-localized to the same norepinephrine-containing secretory granules. High concentrations of NPY have been extracted from the mouse adrenal gland (1243.7 +/- 122.8 pmol NPY/g wet tissue; mean +/- SE). Chromatographic analysis has shown the extracted material to correspond with pure natural NPY.
阿片肽是交感神经去甲肾上腺素能囊泡中的共同递质吗？
影响因子：
64.8
作者：
Wilson,SP;Klein,RL;Chang,KJ;Gasparis,MS;Viveros,OH;Yang,WH
通讯作者：
Yang,WH