Disease epidemiology in arthropods is altered by the presence of nonprotective symbionts.
Disease epidemiology in arthropods is altered by the presence of nonprotective symbionts.
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非保护性共生体的存在改变了节肢动物的疾病流行病学。
DOI：
10.1086/674827
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Ryder JJ
中科院分区：
文献类型：
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作者：
Ryder JJ
遗传的微生物共生体可以调节宿主对天敌攻击的敏感性。更广泛的共生体影响宿主种群的人口统计学，而不改变个人的易感性，有人认为，这些可能会改变宿主疾病的风险，通过改变暴露于天敌的比率。我们提出了这篇论文的第一个测试，特别是测试男性杀死共生体是否改变其宿主携带的性传播感染（STI）的流行病学。性传播感染通常会表现出女性偏见的流行病，我们首先提出了一个简单的模型，表明男性偏见的性传播感染流行病可能会发生在共生体创造女性偏见的人口性别比。然后，我们研究了瓢虫Adalia bipunctata中STI的动态，Adalia bipunctata也是一种雄性杀死细菌的宿主。我们提出的证据表明，男性偏见的性病流行病在自然人群中观察时，男性杀手是常见的。实验室实验并不支持的作用，差异的敏感性男性和女性主机的STI，也没有保护作用的共生体，在创建这种偏见。我们的结论是，可能改变寄生虫流行病学的共生体的范围将比以前设想的要广得多，因为它还包括那些只影响宿主人口统计学的共生体。
Inherited microbial symbionts can modulate host susceptibility to natural enemy attack. A wider range of symbionts influence host population demography without altering individual susceptibility, and it has been suggested that these may modify host disease risk through altering the rate of exposure to natural enemies. We present the first test of this thesis, specifically testing whether male-killing symbionts alter the epidemiology of a sexually transmitted infection (STI) carried by its host. STIs are typically expected to show female-biased epidemics, and we first present a simple model which indicates that male-biased STI epidemics may occur where symbionts create female-biased population sex ratios. We then examined the dynamics of a STI in the ladybird beetleAdalia bipunctata, which is also host to a male-killing bacterium. We present evidence that male-biased epidemics of the STI are observed in natural populations when the male-killer is common. Laboratory experiments did not support a role for differential susceptibility of male and female hosts to the STI, nor a protective role for the symbiont, in creating this bias. We conclude that the range of symbionts likely to alter parasite epidemiology will be much wider than previously envisaged, because it will additionally include those that impact host demography alone.