Influenza D virus infection in Mississippi beef cattle.
Influenza D virus infection in Mississippi beef cattle.
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DOI：
10.1016/j.virol.2015.08.030
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发表时间：
2015-12
期刊：
影响因子：
3.7
通讯作者：
Wan XF
中科院分区：
文献类型：
--
作者：
Ferguson L;Eckard L;Epperson WB;Long LP;Smith D;Huston C;Genova S;Webby R;Wan XF
正粘病毒科的一个新成员，D型流感病毒（IDV），首次在美国中西部地区的猪中报道。本研究旨在扩大我们对IDV流行病学的了解，并确定牛生产系统对病毒传播的影响。从密西西比牛群监测中共回收了15个分离株，两个遗传分支的病毒在同一牛群中共同传播。新生肉牛的血清学评估显示94%的血清阳性，并且假定母体抗体水平在6个月以上的动物中显著较低。主动IDV的传播发生在年轻的地方，断奶，和混合小牛保持。存档血清的血清学表征表明，IDV至少自2004年以来一直在密西西比牛群中传播。需要持续监测IDV在牛群中的演变和流行病学。从密西西比肉牛中共回收到10株D型流感病毒（IDV）。2种抗原性不同的病毒进化枝在同一牛群中共同传播。活动性IDV传播发生在年轻、断奶和混合小牛中。血清学监测表明，IDV至少自2004年以来一直存在于密西西比牛群中。
A new member of the Orthomyxoviridae family, influenza D virus (IDV), was first reported in swine in the Midwest region of the United States. This study aims to extend our knowledge on the IDV epidemiology and to determine the impact of bovine production systems on virus spread. A total of 15 isolates were recovered from surveillance of bovine herds in Mississippi, and two genetic clades of viruses co-circulated in the same herd. Serologic assessment from neonatal beef cattle showed 94% seropositive, and presumed maternal antibody levels were substantially lower in animals over six months of age. Active IDV transmission was shown to occur at locations where young, weaned, and comingled calves were maintained. Serological characterization of archived sera suggested that IDV has been circulating in the Mississippi cattle populations since at least 2004. Continuous surveillance is needed to monitor the evolution and epidemiology of IDV in the bovine population. A total of 10 influenza D viruses (IDVs) were recovered from beef cattle at Mississippi. 2 antigenically distinct clades of viruses co-circulated in the same herd. Active IDV transmission occurs among young, weaned, and comingled calves. Serological surveillance suggests that IDV has been present in the Mississippi cattle population at least since 2004.