Focus on Plasma Medicine
Focus on Plasma Medicine
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DOI：
10.1088/1367-2630/11/11/115011
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发表时间：
2009-11-26
影响因子：
3.3
通讯作者：
Zimmermann, J. L.
中科院分区：
文献类型：
--
作者：
Morfill, G. E.;Kong, M. G.;Zimmermann, J. L.
“等离子体医疗保健”是一个新兴的跨学科研究课题，其重要性迅速增长，在等离子体物理、化学和工程与生命科学的界面上探索了相当多的机会。迄今为止报道的一些科学发现已经在医药、食品安全、环境卫生和化妆品等领域证明了对医疗保健的明显好处。例子包括正在进行的朊病毒灭活、慢性伤口治疗和血浆介导的癌症治疗的研究。目前的研究范围从基本物理过程、等离子体化学设计到等离子体与(1)真核（哺乳动物）细胞的相互作用；㈡原核（细菌）细胞、病毒、孢子和真菌；（三）DNA、脂质、蛋白质和细胞膜；（iv）存在生物流体的活的人类、动物和植物组织。在这个新领域中，各种兴趣是对医院消毒的需求，特别是关于细菌对抗生素耐药性的惊人增长，私人诊所，养老院等的伴随需求，个人卫生方面的应用，以及“设计”等离子体作为可能的药物产品的诱人可能性，使用离子和分子剂进行医疗。反应性等离子体药剂的“输送”发生在气体水平，这意味着不需要载体介质，并且进入处理表面是最佳的。这个焦点问题提供了一个近距离观察在血浆医学的艺术现状与一些前沿的研究文章，以及介绍性审查。
'Plasma Healthcare' is an emerging interdisciplinary research topic of rapidly growing importance, exploring considerable opportunities at the interface of plasma physics, chemistry and engineering with life sciences. Some of the scientific discoveries reported so far have already demonstrated clear benefits for healthcare in areas of medicine, food safety, environmental hygiene, and cosmetics. Examples include ongoing studies of prion inactivation, chronic wound treatment and plasma-mediated cancer therapy. Current research ranges from basic physical processes, plasma chemical design, to the interaction of plasmas with (i) eukaryotic (mammalian) cells; (ii) prokaryotic (bacteria) cells, viruses, spores and fungi; (iii) DNA, lipids, proteins and cell membranes; and (iv) living human, animal and plant tissues in the presence of biofluids. Of diverse interests in this new field is the need for hospital disinfection, in particular with respect to the alarming increase in bacterial resistance to antibiotics, the concomitant needs in private practices, nursing homes etc, the applications in personal hygiene-and the enticing possibility to 'design' plasmas as possible pharmaceutical products, employing ionic as well as molecular agents for medical treatment. The 'delivery' of the reactive plasma agents occurs at the gaseous level, which means that there is no need for a carrier medium and access to the treatment surface is optimal. This focus issue provides a close look at the current state of the art in Plasma Medicine with a number of forefront research articles as well as an introductory review.