Chemoselective Hydrogenation Catalyzed by Pd on Spherical Carbon
Chemoselective Hydrogenation Catalyzed by Pd on Spherical Carbon
复制标题
DOI：
10.1002/cctc.201300639
复制
发表时间：
2013-12-01
期刊：
影响因子：
4.5
通讯作者：
Sajiki, Hironao
中科院分区：
文献类型：
--
作者：
Esaki, Hiroyoshi;Hattori, Tomohiro;Sajiki, Hironao
我们开发了一种高化学选择性的加氢方法，使用球形碳负载的新型钯催化剂（0.5% Pd/SC）。0.5% Pd/SC表现出新的催化活性，可以实现炔烃、烯烃、氮化物、硝基和脂肪族o -叔丁基二甲基硅基（TBS）醚的化学选择性加氢，而不催化苯酯、苯醚、腈、芳香酮、n -碳苄基氧基（N-Cbz）保护基团和芳香O-TBS醚的氢解。
We have developed a highly chemoselective hydrogenation method using a novel palladium catalyst supported on spherical carbon (0.5% Pd/SC). The 0.5% Pd/SC exhibited a novel catalytic activity and could achieve the chemoselective hydrogenation of alkynes, alkenes, azides, nitro groups, and aliphatic O-tert-butyldimethylsilyl (TBS) ethers without hydrogenolysis of benzyl esters, benzyl ethers, nitriles, aromatic ketones, N-carbobenzyloxy (N-Cbz) protective groups, and aromatic O-TBS ethers.