LIPOSOMAL AMPHOTERICIN-B (AMBISOME) FOR TREATMENT OF CUTANEOUS WIDESPREAD CANDIDOSIS IN AN INFANT WITH METHYLMALONIC ACIDEMIA
LIPOSOMAL AMPHOTERICIN-B (AMBISOME) FOR TREATMENT OF CUTANEOUS WIDESPREAD CANDIDOSIS IN AN INFANT WITH METHYLMALONIC ACIDEMIA
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DOI：
10.1007/bf01957220
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发表时间：
1993-12-01
影响因子：
3.6
通讯作者：
MULLER, W
中科院分区：
文献类型：
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作者：
STOCKLER, S;LACKNER, H;MULLER, W
在一个10周大的婴儿与维生素b12反应性甲基丙二酸血症，皮肤念珠菌病（白色念珠菌）进展迅速，尽管局部抗真菌治疗。经两性霉素- b （AmBisome）脂质体静脉治疗1周后，皮炎完全消失，血培养无菌。未观察到任何副作用。这是用这种新的抗真菌药物治疗婴儿的第一次经验之一。
In a 10-week-old infant with vitamin B12-unresponsive methylmalonic acidaemia, cutaneous candidosis (Candida albicans) progressed rapidly despite topical antifungal treatment. After 1 week of intravenous therapy with liposomal amphotericin-B (AmBisome) the dermatitis disappeared completely and blood cultures were sterile. No side-effects were observed. This is one of the first experiences in the treatment of infants with this new antifungal agent.