Metal-ion regulation of gene expression in yeast.
Metal-ion regulation of gene expression in yeast.
复制标题
DOI：
10.1016/s1367-5931(98)80063-x
复制
发表时间：
1998-04
影响因子：
7.8
通讯作者：
D. R. Winge;L. T. Jensen;Chandra Srinivasan
中科院分区：
文献类型：
--
作者：
D. R. Winge;L. T. Jensen;Chandra Srinivasan
Metal-responsive transcription factors exist in yeast to modulate expression of genes that encode proteins involved in cellular uptake of copper, iron and zinc ions. These signal transduction pathways function in the cellular regulation of the intracellular concentration of free metal ions. A second component of metal homeostasis is the regulation of metal-ion binding through protein-mediated metallation. Copper-specific chaperones exist in yeast that route copper ions to the site of biosynthesis of copper-metalloenzymes.
