Prognostic Significance of Insomnia in Heart Failure
Prognostic Significance of Insomnia in Heart Failure
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DOI：
10.1253/circj.cj-16-0205
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发表时间：
2016-07-01
影响因子：
3.3
通讯作者：
Takeishi, Yasuchika
中科院分区：
文献类型：
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作者：
Kanno, Yuki;Yoshihisa, Akiomi;Takeishi, Yasuchika
背景资料：失眠与心力衰竭（HF）事件有关，但失眠对HF的临床意义和影响尚不清楚。方法和结果：将1,011例因HF入院的患者按是否存在失眠分为2组：HF伴失眠组（失眠组，n=519）和HF不伴失眠组（非失眠组，n=492）。我们比较了（1）心脏事件发生率，包括心源性死亡和HF恶化;（2）基础临床背景，包括实验室数据、超声心动图数据和2组之间的心肺运动试验。Kaplan-Meier分析显示，失眠组的心脏事件发生率显著高于非失眠组（39.1% vs. 23.4%，P
Background: Insomnia is associated with incident heart failure (HF), but the clinical significance and impact of insomnia on HF remain unclear.Methods and Results: Consecutive 1,011 patients admitted for HF were divided into 2 groups according to the presence of insomnia: HF with insomnia (insomnia group, n=519) and HF without insomnia (non-insomnia group, n=492). We compared (1) cardiac event rates including cardiac death and worsening HF; and (2) underlying clinical background including laboratory data, echocardiographic data, and cardiopulmonary exercise test between the 2 groups. On Kaplan-Meier analysis, cardiac event rate was significantly higher in the insomnia group than in the noninsomnia group (39.1 vs. 23.4%, P