Comparing HIV Post-Exposure Prophylaxis, Testing, and New Diagnoses in Two Australian Cities with Different Lockdown Measures during the COVID-19 Pandemic.
Comparing HIV Post-Exposure Prophylaxis, Testing, and New Diagnoses in Two Australian Cities with Different Lockdown Measures during the COVID-19 Pandemic.
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DOI：
10.3390/ijerph182010814
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发表时间：
2021-10-14
影响因子：
--
通讯作者：
Fairley CK
中科院分区：
文献类型：
--
作者：
Chow EPF;Ong JJ;Donovan B;Foster R;Phillips TR;McNulty A;Fairley CK
为应对COVID-19大流行，澳大利亚于2020年3月22日实施了全国封锁。墨尔本，而不是悉尼，在2020年7月至10月期间进行了第二次COVID-19封锁。我们比较了这些封锁期间艾滋病毒暴露后预防（PEP）处方、艾滋病毒检测和新艾滋病毒诊断的数量。使用发病率比将2020年的三个结果与2019年进行比较。墨尔本和悉尼的PEP处方分别减少了37%和46%，在封城期间减少幅度更大（墨尔本第一次和第二次封城期间减少了68%和57%，悉尼封城期间减少了60%）。墨尔本和悉尼的艾滋病毒检测分别减少了41%和32%，在封锁期间减少幅度更大（墨尔本第一次和第二次封锁期间减少了57%和61%，悉尼封锁期间减少了58%）。墨尔本和悉尼的新艾滋病毒诊断分别减少了44%和47%，但在封锁期间没有显著减少。在封锁期间，PEP处方、艾滋病毒检测和新艾滋病毒诊断的减少可能是由于在此期间性伴侣数量的减少。由于在COVID-19封锁期间艾滋病毒预防措施的大幅减少，这也可能导致更多的艾滋病毒传播。
Australia introduced a national lockdown on 22 March 2020 in response to the COVID-19 pandemic. Melbourne, but not Sydney, had a second COVID-19 lockdown between July and October 2020. We compared the number of HIV post-exposure prophylaxis (PEP) prescriptions, HIV tests, and new HIV diagnoses during these lockdown periods. The three outcomes in 2020 were compared to 2019 using incidence rate ratio. There was a 37% and 46% reduction in PEP prescriptions in Melbourne and Sydney, respectively, with a larger reduction during lockdown (68% and 57% reductions in Melbourne’s first and second lockdown, 60% reduction in Sydney’s lockdown). There was a 41% and 32% reduction in HIV tests in Melbourne and Sydney, respectively, with a larger reduction during lockdown (57% and 61% reductions in Melbourne’s first and second lockdowns, 58% reduction in Sydney’s lockdown). There was a 44% and 47% reduction in new HIV diagnoses in Melbourne and Sydney, respectively, but no significant reductions during lockdown. The reduction in PEP prescriptions, HIV tests, and new HIV diagnoses during the lockdown periods could be due to the reduction in the number of sexual partners during that period. It could also result in more HIV transmission due to substantial reductions in HIV prevention measures during COVID-19 lockdowns.
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