Ubiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradation.

Ubiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradation.
复制标题

泛素样和泛素相关结构域蛋白质:蛋白酶体降解的重要性。

DOI:
10.1007/s00018-009-0048-9
复制
发表时间:
2009-09
影响因子:
8
通讯作者:
Lau, Alan F.
Lau, Alan F.
中科院分区:
生物学1区
文献类型:
--
作者:
Su, Vivian;Lau, Alan F.

文献摘要

参考文献

被引文献

相似文献

蛋白质降解的泛素-蛋白酶体途径是参与维持细胞蛋白质适当水平的主要机制之一。因此,蛋白酶体降解的调节确保了适当的细胞功能。含有泛素样(UbL)和泛素相关(乌巴)结构域的蛋白质家族与蛋白酶体降解有关。含有UbL-UBA结构域的蛋白质与预定降解的底物以及蛋白酶体的亚基缔合,从而调节蛋白质的适当周转。
The ubiquitin–proteasome pathway of protein degradation is one of the major mechanisms that are involved in the maintenance of the proper levels of cellular proteins. The regulation of proteasomal degradation thus ensures proper cell functions. The family of proteins containing ubiquitin-like (UbL) and ubiquitin-associated (UBA) domains has been implicated in proteasomal degradation. UbL–UBA domain containing proteins associate with substrates destined for degradation as well as with subunits of the proteasome, thus regulating the proper turnover of proteins.
DOI: 10.1038/sj.onc.1207540
发表时间: 2004-05-20
期刊: ONCOGENE
影响因子: 8
作者:
Brignone, C;Bradley, KE;Grossman, SR
通讯作者: Grossman, SR
DOI: 10.1016/j.bbrc.2008.06.082
发表时间: 2008-09-12
影响因子: 3.1
作者:
Geetha, Thangiah;Seibenhener, M. Lamar;Chen, Li;Madura, Kiran;Wooten, Marie W.
通讯作者: Wooten, Marie W.
DOI: 10.1111/j.1471-4159.2005.03181.x
发表时间: 2005-07-01
影响因子: 4.7
作者:
Babu, JR;Geetha, T;Wooten, MW
通讯作者: Wooten, MW
p62/SQSTM1形成自噬降解的蛋白质聚集体,并对亨廷顿蛋白诱导的细胞死亡具有保护作用。
DOI: 10.1083/jcb.200507002
发表时间: 2005-11-21
影响因子: 7.8
作者:
Bjorkoy, Geir;Lamark, Trond;Brech, Andreas;Outzen, Heidi;Perander, Maria;Overvatn, Aud;Stenmark, Harald;Johansen, Terje
通讯作者: Johansen, Terje
DOI: 10.1128/mcb.23.24.8960-8969.2003
发表时间: 2003-12-01
影响因子: 5.3
作者:
Glockzin, S;Ogi, FX;Blattner, C
通讯作者: Blattner, C