A Small-Footprint, High-Capacity Flow Reactor for UV Photochemical Synthesis on the Kilogram Scale
A Small-Footprint, High-Capacity Flow Reactor for UV Photochemical Synthesis on the Kilogram Scale
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DOI：
10.1021/acs.oprd.6b00277
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发表时间：
2016-10-01
影响因子：
3.4
通讯作者：
Booker-Milburn, Kevin I.
中科院分区：
文献类型：
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作者：
Elliott, Luke D.;Berry, Malcolm;Booker-Milburn, Kevin I.
描述了用于合成有机光化学的高度紧凑和强大的反应器的开发，其能够使反应时间减少10倍，并且比以前的氟化乙烯丙烯管式反应器的功率效率高出高达30%。两个反应在24小时内得到超过1 kg的产物。另外两个反应在24小时内的生产率为4和8 kg。该反应器由一系列串联在一起的石英管组成，并围绕可变功率汞灯轴向排列。这种紧凑且相对简单的设备可以在标准通风柜中安全运行。
The development of a highly compact and powerful reactor for synthetic organic photochemistry is described enabling a 10-fold reduction in reaction times, with up to 30% more power efficiency than previous fluorinated ethylene propylene tube reactors. Two reactions gave over 1 kg of product in 24 h. Two other reactions had productivities of 4 and 8 kg in 24 h. The reactor consists of a succession of quartz tubes connected together in series and arranged axially around a variable power mercury lamp. This compact and relatively simple device can be safely operated in a standard fumehood.