Prediction of hearing recovery in sudden deafness treated with intratympanic steroids.
Prediction of hearing recovery in sudden deafness treated with intratympanic steroids.
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DOI：
10.14639/0392-100x-1614
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发表时间：
2018-10
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影响因子：
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通讯作者：
De Vincentiis M
中科院分区：
文献类型：
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作者：
Attanasio G;Russo FY;Di Porto E;Cagnoni L;Masci E;Ralli M;Greco A;De Vincentiis M
本研究的目的是获得一个概率模型，允许预测突发感音神经性听力损失患者的听力恢复只与鼓室内类固醇治疗。对381例患者进行了单中心回顾性病历审查。使用Probit模型研究治疗成功（根据Furuashi标准的显著或完全恢复）与疾病发作和治疗开始之间的延迟之间的相关性。分析中包括患者的年龄和听力曲线形状。结果表明，延迟与变量成功负相关。考虑到整个样本，每延迟一天，成功的概率就会降低3%。预测模型显示，从疾病发作开始的每一天，在没有药物治疗的情况下，成功的概率都会下降，因此我们得出结论，强烈建议早期治疗。
The present study aims to obtain a probability model allowing prediction of auditory recovery in patients affected by sudden sensorineural hearing loss treated exclusively with intratympanic steroids. A monocentric retrospective chart review of 381 patients has been performed. A Probit model was used to investigate the correlation between the success of treatment (marked or total recovery according to Furuashi’s criteria) and the delay between onset of disease and beginning of therapy. The age of patients and audiometric curve shapes were included in the analysis. The results show that delay is negatively correlated with variable success. Considering the entire sample, each day of delay decreases the probability of success by 3%. The prediction model shows that for each day that passes from the onset of the disease the probability of success declines in absence of the medical treatment, hence we conclude that early treatment is strongly recommended.