Barriers to early uptake of tetanus, diphtheria and acellular pertussis vaccine (Tdap) among adults-United States, 2005-2007

Barriers to early uptake of tetanus, diphtheria and acellular pertussis vaccine (Tdap) among adults-United States, 2005-2007
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DOI:
10.1016/j.vaccine.2011.03.058
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发表时间:
2011-05-17
期刊:
影响因子:
5.5
通讯作者:
Ahmed, Faruque
Ahmed, Faruque
中科院分区:
医学3区
文献类型:
--
作者:
Miller, Brady L.;Kretsinger, Katrina;Ahmed, Faruque

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背景资料:破伤风,白喉和无细胞百日咳疫苗(Tdap)是由免疫实践咨询委员会(ACIP)于2005年推荐给美国成年人的。我们的目标是确定障碍早期摄取Tdap成人population.Methods:2007年全国免疫调查(NIS)-成人是一个电话调查主办的疾病控制和预防中心(CDC)。收集了年龄≥ 18岁的人接种ACIP推荐的所有疫苗的信息。加权分析解释了复杂的调查设计和无响应。结果:总体而言,3.6%的18-64岁成年人报告接种了Tdap疫苗。在未接种疫苗的受访者中,18.8%的人听说过Tdap,其中9.4%的人报告说医疗保健提供者推荐了它。感染百日咳的低风险是不接种Tdap或不愿意接种的最常见原因(44.7%)。大多数未接种疫苗的受访者(81.8%)表示愿意接受Tdap,如果它是由provider.Conclusions建议:在头两年的可用性,Tdap摄取可能会抑制Tdap的低集体意识和低感知风险的美国成年人之间的百日咳合同,以及缺乏提供者对患者的疫苗接种建议。由于许多成年人愿意接受疫苗接种,因此扩大覆盖面的潜力很大。爱思唯尔有限公司出版
Background: The tetanus, diphtheria and acellular pertussis vaccine (Tdap) was recommended by the Advisory Committee on Immunization Practices (ACIP) for U.S. adults in 2005. Our objective was to identify barriers to early uptake of Tdap among adult populations.Methods: The 2007 National Immunization Survey (NIS)-Adult was a telephone survey sponsored by the Centers for Disease Control and Prevention (CDC). Immunization information was collected for persons aged >= 18 years on all ACIP-recommended vaccines. A weighted analysis accounted for the complex survey design and non-response.Results: Overall, 3.6% of adults aged 18-64 years reported receipt of a Tdap vaccination. Of unvaccinated respondents, 18.8% had heard of Tdap, of which 9.4% reported that a healthcare provider had recommended it. A low perceived risk of contracting pertussis was the single most common reason for either not vaccinating with Tdap or being unwilling to do so (44.7%). Most unvaccinated respondents (81.8%) indicated a willingness to receive Tdap if it was recommended by a provider.Conclusions: During the first two years of availability, Tdap uptake was likely inhibited by a low collective awareness of Tdap and a low perceived risk of contracting pertussis among U.S. adults, as well as a paucity of provider-to-patient vaccination recommendations. Significant potential exists for improved coverage, as many adults were receptive to vaccination. Published by Elsevier Ltd.