Cerebral motor control in patients with gliomas around the central sulcus studied with spatially filtered magnetoencephalography
Cerebral motor control in patients with gliomas around the central sulcus studied with spatially filtered magnetoencephalography
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DOI：
10.1136/jnnp.2002.001834
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发表时间：
2004-03-01
影响因子：
11
通讯作者：
Yoshimine, T
中科院分区：
文献类型：
--
作者：
Taniguchi, M;Kato, A;Yoshimine, T
目的：空间滤波脑磁图（MEG）的应用，以探讨在中央沟周围肿瘤患者的大脑运动控制的机制的变化：MEG记录在重复的手抓任务在6例中央沟周围的胶质瘤和4个对照组。使用合成孔径磁力测定法对运动任务（事件相关去极化，ERD）期间α（8-13 Hz）、β（13-30 Hz）和低γ波段（30-50 Hz）的功率降低进行统计学分析。ERD的断层扫描叠加在个人的磁共振images.Results：B ERD始终定位于对侧的初级感觉运动皮层（MI/SI）在对照组，而α和低γ ERD表现出相当大的受试者间的变异性。在非受影响的侧手运动的患者β ERD也定位于对侧MI/SI，但专门到同侧半球在受影响的侧手movement.Conclusions：ERD在患者组的改变模式在受影响的侧手运动表明招聘不同的运动区，特别是同侧MI/SI，这可能是需要有效的运动受影响的手。
Objective: Application of spatially filtered magnetoencephalography (MEG) to investigate changes in the mechanism of cerebral motor control in patients with tumours around the central sulcus.Methods: MEG records were made during a repetitive hand grasping task in six patients with gliomas around the central sulcus and in four control subjects. Power decreases in the alpha (8-13 Hz), beta (13-30 Hz), and low gamma bands (30-50 Hz) during the motor tasks (event related desynchronisation, ERD) were analysed statistically with synthetic aperture magnetometry. The tomography of ERD was superimposed on the individual's magnetic resonance image.Results: b ERD was consistently localised to the contralateral primary sensorimotor cortex (MI/SI) in control subjects, whereas the alpha and low gamma ERD showed considerable intersubject variability. beta ERD in patients during non-affected side hand movement was also localised to the contralateral MI/SI, but exclusively to the ipsilateral hemisphere during affected side hand movement.Conclusions: The altered pattern of ERD in the patient group during affected side hand movement suggests recruitment of diverse motor areas, especially the ipsilateral MI/SI, which may be required for the effective movement of the affected hand.