Sex differences in the poly somnographic sleep of young adults: a community-based study
Sex differences in the poly somnographic sleep of young adults: a community-based study
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DOI：
10.1016/j.sleep.2005.05.008
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发表时间：
2006-01-01
期刊：
影响因子：
4.8
通讯作者：
Breslau, N
中科院分区：
文献类型：
--
作者：
Roehrs, T;Kapke, A;Breslau, N
背景和目的：在小规模的临床样本中，男性的慢波睡眠比女性少。鉴于男性与睡眠有关的呼吸障碍的患病率较高，本研究评估了大量非临床成人样本中睡眠的性别差异，并控制了原发性睡眠障碍。患者和方法：从密歇根州东南部的纵向样本中抽取31-40岁的男性和女性作为研究对象。每个人都进行了一项睡眠研究，包括连续两个8小时的标准多导睡眠图（NPSG）和中间一天的多次睡眠潜伏期测试（MSLT）。结果：在439名符合条件的参与者中，292名（66.5%）同意在睡眠实验室连续度过两个晚上和中间的一天。每晚收集监测呼吸和腿部运动的标准多导睡眠图，并在中间一天进行MSLT。男性比女性有更多与睡眠有关的呼吸障碍。在调整了较高的呼吸障碍患病率后，男性的平均睡眠效率（即醒着的时间增加）仍然较低，第一阶段睡眠的比例较高。男性和女性在大多数其他睡眠参数上没有差异，在MSLT上白天的困倦程度上也没有差异。结论：睡眠相关的呼吸障碍是睡眠性别差异的部分原因。在排除了呼吸障碍后，男性的睡眠质量仍然较低，效率也较低，但这与白天更嗜睡无关。这是否反映了睡眠平衡器功能的性别差异，还需要进一步研究。(c) 2005 Elsevier B.V.版权所有
Background and purpose: In small, clinical samples, men have reduced slow wave sleep compared to women. Given the higher prevalence of sleep-related breathing disturbance in men, this study assessed sex differences in sleep in a large, non-clinical sample of adults and controlled for primary sleep disorders.Patients and methods: Men and women, 31-40 years old, drawn from a longitudinal sample representative of southeast Michigan served as subjects. Each underwent a sleep study consisting of two consecutive 8-h nights of standard polysomnography (NPSG) and a multiple sleep latency test (MSLT) the intervening day.Results: Of the 439 eligible participants, 292 (66.5%) agreed to spend two consecutive nights and the intervening day in the sleep laboratory. Standard polysomnograms that monitored respiration and leg movements were collected each night, and on the intervening day the MSLT was performed. Men had more sleep-related breathing disturbance than women. After adjusting for this higher prevalence of respiratory disturbance, men still had a lower mean sleep efficiency (i.e. increased wake time) and a higher percentage of stage 1 sleep. Men and women did not differ in most other sleep parameters and did not differ in level of daytime sleepiness on the MSLT.Conclusions: Sleep-related respiratory disturbance accounted for some of the sex differences in sleep. After correcting for respiratory disturbance, men still had lighter and less efficient sleep, but this was not associated with greater daytime sleepiness. Whether this reflects a sex difference in the functioning of the sleep homeostat will require further study. (c) 2005 Elsevier B.V. All rights reserved.