High-speed optical coherence tomography for management after laser in situ keratomileusis
High-speed optical coherence tomography for management after laser in situ keratomileusis
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DOI：
10.1016/j.jcrs.2006.07.015
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发表时间：
2006-11-01
影响因子：
2.8
通讯作者：
Huang, David
中科院分区：
文献类型：
--
作者：
Avila, Mariana;Li, Yan;Huang, David
目得：目的：探讨光学相干断层扫描（OCT）在准分子激光原位角膜磨镶术（LASIK）相关问题中的应用。单位：美国南加州大学凯克医学院眼科研究所和眼科系，洛杉矶，加州，USA。临床检查，超声（US）测厚，Placido环裂隙扫描角膜地形图（Orbscan II，博士伦），和高速角膜OCT进行了performed.Results：在回归和角膜扩张的情况下，OCT提供角膜，皮瓣，和后基质床的厚度测量。在一个有再切增强并发症的病例中，确定了组织缺损和皮瓣界面平面的位置。这些信息用于确定进一步激光消融是否安全，确认角膜扩张和管理并发症。中央角膜厚度的光学相干断层扫描测量结果与美国角膜厚度测量结果吻合良好（差异为6.4 μ m +/- 11.7 [SD]）（P =.026），而Orbscan显著低估了角膜厚度（-67.5 +/- 72.5 μ m）（P =.17）。对LASIK术后疗效监测及并发症的评估有重要意义。
PURPOSE: To report applications of optical coherence tomography (OCT) in the management of laser in situ keratomileusis (LASIK) related problems.SETTING: Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.METHODS: Five patients referred for LASIK-related problems were enrolled in a prospective observational study. Clinical examination, ultrasound (US) pachymetry, Placido ring slit-scanning corneal topography (Orbscan II, Bausch & Lomb), and high-speed corneal OCT were performed.RESULTS: In cases of regression and keratectasia, OCT provided thickness measurements of the cornea, flap, and posterior stromal bed. Locations of tissue loss and flap interface planes were identified in a case with a recut enhancement complication. The information was used to determine whether further laser ablation was safe, confirm keratectasia, and manage complications. Optical coherence tomography measurements of central corneal thickness agreed well with US pachymetry measurements (difference 6.4 mu m +/- 11.7 [SD]) (P =.026), while Orbscan significantly underestimated corneal thickness (-67.5 +/- 72.5 mu m) (P =.17).CONCLUSIONS: High-speed OCT provided noncontact imaging and measurement of LASIK anatomy. It was useful in monitoring LASIK results and evaluating complications.