SYMPTOMATIC ABNORMALITIES OF DARK-ADAPTATION IN PATIENTS WITH AGE-RELATED BRUCHS MEMBRANE CHANGE
SYMPTOMATIC ABNORMALITIES OF DARK-ADAPTATION IN PATIENTS WITH AGE-RELATED BRUCHS MEMBRANE CHANGE
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DOI：
10.1136/bjo.77.9.549
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发表时间：
1993-09-01
影响因子：
4.1
通讯作者：
BIRD, AC
中科院分区：
文献类型：
--
作者：
STEINMETZ, RL;HAIMOVICI, R;BIRD, AC
一些与年龄相关的Bruch膜水平改变且视力良好的患者报告在暗光下视力低下，在强光下视力衰退，在黑暗中可见明显的中央暗点。记录12例12只眼的眼科检查、暗视阈值和暗适应动力学。9名受试者在荧光素血管造影术中均有黄斑玻璃斑弱荧光，6名受试者荧光素血管造影术显示脉络膜充盈延长。在6名患者中，暗点阈值被压低，这些患者都在黑暗中或夜间视力不佳时经历了中央暗点。所有10例患者的暗适应动力学都是异常的，在这些患者中，可以进行可靠的测量。这些结果表明，视觉症状反映了年龄相关性Bruchs膜改变患者的暗视敏感度和暗适应时间进程的异常。
Some patients with age-related changes at the level of Bruch's membrane and good visual acuity report poor vision in dim light, fading vision in bright light, and a central scotoma noticeable in the dark. Ophthalmic examination, scotopic thresholds, and dark adaptation kinetics were recorded in 12 eyes of 12 patients with such symptoms. All had macular drusen which were hypofluorescent on fluorescein angiography in nine subjects, and six had evidence of prolonged choroidal filling on fluorescein angiography. Scotopic thresholds were depressed in six patients who all experienced a central scotoma in the dark or poor night vision. The kinetics of dark adaptation were abnormal in all 10 patients in whom reliable measurements were possible. The findings suggest that visual symptoms reflect abnormality of both scotopic sensitivity and the time course of dark adaptation in patients with age-related Bruch's membrane change.