An update on concurrent malaria and typhoid fever in Cameroon
An update on concurrent malaria and typhoid fever in Cameroon
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DOI：
10.1016/s0035-9203(99)90282-1
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发表时间：
1999-03-01
影响因子：
2.2
通讯作者：
Deas, JE
中科院分区：
文献类型：
--
作者：
Ammah, A;Nkuo-Akenji, T;Deas, JE
疟疾和伤寒是喀麦隆的地方病，症状和体征重叠。虽然疟疾的高流行率是一个既定事实，但只是在过去五年中，才有异常多的疾病被诊断为疟疾与伤寒并存。肥达试验被广泛用作诊断伤寒的唯一实验室试验。为了调查疟疾和伤寒的关联程度，我们使用血和粪便培养作为伤寒的附加诊断试验。我们报告说，200例发热患者中，17.0%并发疟疾和伤寒（伤寒沙门氏菌）的细菌学确诊的基础上，相比之下，47.9%的肥达试验。较高比例的患者（32.5%）同时患有疟疾和S。与S.副伤寒（2%）和沙门氏菌（2%）。伤寒（P < 0.05）。我们的结论是，诊断为疟疾与伤寒油炸锅共存的发热病例的数量被高估。
Malaria and typhoid fever are endemic diseases in Cameroon, with overlapping signs and symptoms. While the high prevalence of malaria is an established fact, it is only within the past 5 years that an unusually high number of illnesses have been diagnosed as malaria co-existing with typhoid fever. The Widal test is widely used as the sole laboratory test for the diagnosis of typhoid fever. To investigate the extent of the malaria and typhoid fever association, we used blood and stool cultures as additional diagnostic tests for typhoid fever. We report that, of 200 patients presenting with fever, 17.0% had concurrent malaria and typhoid fever (Salmonella typhi) based on bacteriological proven diagnosis as compared with 47.9% based on the Widal test. A higher proportion of patients (32.5%) had malaria coexisting with S. typhimurium when compared to S. paratyphi (2%) and S. typhi(P < 0.05). We conclude that the number of fever cases diagnosed as malaria co-existing with typhoid fryer is overestimated.