Polyvascular Disease: Reappraisal of the Current Clinical Landscape.
Polyvascular Disease: Reappraisal of the Current Clinical Landscape.
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DOI：
10.1161/circinterventions.119.007385
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发表时间：
2019-12
期刊：
影响因子：
--
通讯作者：
Jones WS
中科院分区：
文献类型：
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作者：
Gutierrez JA;Aday AW;Patel MR;Jones WS
两个或多个动脉床内的动脉粥样硬化被称为“多血管疾病”。虽然多血管疾病长期以来一直与心血管风险增加有关，但关于其病理生理学和管理仍有许多未知之处。在过去的十年中，心血管疾病领域在旨在减轻缺血事件的抗血栓形成和降脂治疗方面经历了指数增长。本综述描述了当代观察性和临床试验人群中与多血管疾病相关的固有风险，并总结了该高危人群的新型治疗方法。
Atherosclerosis within two or more arterial beds has been termed “polyvascular disease”. Although polyvascular disease has long been associated with heightened cardiovascular risk, much is still unknown regarding its pathophysiology and management. In this past decade the field of cardiovascular disease has experienced exponential growth in terms of antithrombotic and lipid-lowering therapies aimed at mitigating ischemic events. This review describes the inherent risk associated with polyvascular disease in contemporary observational and clinical trial populations, and summarizes novel therapies in this high-risk population.