Systemic Lupus Erythematosus in an African Caribbean Population: Incidence, Clinical Manifestations, and Survival in the Barbados National Lupus Registry
Systemic Lupus Erythematosus in an African Caribbean Population: Incidence, Clinical Manifestations, and Survival in the Barbados National Lupus Registry
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DOI：
10.1002/acr.21656
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发表时间：
2012-08-01
影响因子：
4.7
通讯作者：
Liang, Matthew H.
中科院分区：
文献类型：
--
作者：
Flower, Cindy;Hennis, Anselm J. M.;Liang, Matthew H.
Objective.评估系统性红斑狼疮（SLE）在巴巴多斯主要是非洲加勒比人口中的流行病学、临床特征和结局。2007年建立了所有诊断为SLE患者的国家登记处。通过与岛上唯一的风湿病学服务机构、医生和狼疮倡导组织的合作，促进了完整的病例确定。入选研究需要知情同意。2000年1月1日至2009年12月31日期间，有183例SLE新发病例（98%为非洲加勒比人），影响172名女性和11名男性，未调整的年发病率为12.21（95%置信区间[95% CI] 10.46-14.18）和0.84（95% CI 0.42-1.51）/100，000人-年。不包括儿科病例（年龄
Objective. To assess the epidemiology, clinical features, and outcomes of systemic lupus erythematosus (SLE) in the predominantly African Caribbean population of Barbados.Methods. A national registry of all patients diagnosed with SLE was established in 2007. Complete case ascertainment was facilitated by collaboration with the island's sole rheumatology service, medical practitioners, and the lupus advocacy group. Informed consent was required for inclusion.Results. Between January 1, 2000 and December 31, 2009, there were 183 new cases of SLE (98% African Caribbean) affecting 172 women and 11 men for unadjusted annual incidence rates of 12.21 (95% confidence interval [95% CI] 10.46-14.18) and 0.84 (95% CI 0.42-1.51) per 100,000 person-years, respectively. Excluding pediatric cases (ages