HPD photoradiation therapy for cancer at Kingston and Hamilton.
HPD photoradiation therapy for cancer at Kingston and Hamilton.
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金斯顿和汉密尔顿的 HPD 癌症光放射疗法。
DOI：
10.1007/978-1-4684-4406-3_7
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发表时间：
1983
影响因子：
--
通讯作者：
J. Kennedy
中科院分区：
文献类型：
--
作者：
J. Kennedy
本文所附的表格总结了我们从1978年4月至今的光照射治疗经验。相对响应性的评价基于以下考虑因素。5+级意味着肿瘤可以被一定剂量的光摧毁，只会引起轻微的红斑和轻微的水肿；3+等级表明，破坏皮下结节所需的最小光剂量可能会造成中等程度的皮肤损伤；2+等级意味着预期的皮肤损伤程度将处于可接受和不可接受之间的边界；1+的评分表明，如果要成功地使用外束治疗皮下结节，严重的皮肤损伤是不可避免的。这些相对反应性的评估只是近似值，因为肿瘤肿块对治疗的反应取决于肿块的体积及其在皮肤内或皮肤下的深度以及其组织学。由于我们治疗过的所有基底细胞癌都是相对浅表的，并且由于乳腺癌的小而浅表的皮内结节对相对低剂量的光激活光反应非常好，因此乳腺癌的绝对反应性可能与基底细胞癌非常相似。
The Table accompanying this article summarizes our experience with photoradiation therapy from April 1978 to the present. Evaluation of relative responsiveness was based on the following considerations. A 5+ rating means that the tumor can be destroyed by a dose of light that will cause only mild erythema and slight edema; a 3+ rating indicates that a moderate amount of skin damage may be expected from the minimum dose of light required to destroy a subcutaneous nodule; a 2+ rating means that the degree of skin damage to be expected will be on the border between acceptable and not acceptable; and a 1+ rating indicates that serious skin damage is inevitable if a subcutaneous nodule is to be treated successfully by external beam. These evaluations of relative responsiveness are only approximate, since the response of a tumor mass to treatment depends upon the volume of the mass and its depth within or below the skin as well as upon its histology. Since all of the basal cell carcinomas we have treated have been relatively superficial, and since small and superficial intracutaneous nodules of breast carcinoma respond very well to relatively low doses of photoactivating light, the responsiveness of breast carcinoma in absolute terms may well be very similar to that of basal cell carcinomas.