Utility of SAECG in arrhythmogenic right ventricle dysplasia.
Utility of SAECG in arrhythmogenic right ventricle dysplasia.
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SAECG 在致心律失常性右心室发育不良中的应用。
DOI：
10.1046/j.1542-474x.2003.08204.x
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Calkins,Hugh
中科院分区：
文献类型：
--
作者：
Nasir,Khurram;Rutberg,Julie;Tandri,Harikrishna;Berger,Ronald;Tomaselli,Gordon;Calkins,Hugh
背景：致心律失常性右心室发育不良（ARVD）的特点是右心室心肌逐渐被纤维脂肪组织替代，这被认为是导致 SAECG 检测到晚电位（LP）存在的原因。关于 SAECG 在 ARVD 患者的诊断和预后中的作用尚缺乏普遍共识。本系统综述的目的是更好地定义 SAECG 在 ARVD 中的作用。方法：对文献进行广泛回顾，具体描述 ARVD 中 LP 的患病率及其决定因素，探索可提高 SAECG 诊断能力的各种选择，并为正确使用该技术提供建议。结果：LP 在 ARVD 中常见（47-100%），在 ARVD 中更常见。 严重疾病和有自发性 VT 记录的患者。 SAECG 是追踪疾病特征演变的有用测试。 4-16% 的 ARVD 患者的正常家庭成员也有异常的 SAECG 结果。通过采用 25 Hz 高通滤波器并专门寻找 Z 导联的变化，可以改善 ARVD 中 LP 的检测。结论：SAECG 测试应被视为评估已知或疑似 ARVD 患者的标准部分。需要进一步的研究来证实 SAECG 检测在预测心律失常风险和评估疾病进展率方面的价值，并确定 ARVD 患者家庭成员中 SAECG 异常的患病率较高是否代表 ARVD 的早期检测。正在进行的右心室发育不良的多学科研究有望回答其中一些问题。
Background:Arrhythmogenic right ventricular dysplasia (ARVD) is characterized by progressive replacement of RV myocardium with fibro‐adipose tissue thought to be responsible for the presence of late potentials (LP) detected by SAECG. The general consensus on the role of SAECG in the diagnosis and prognosis of patients with ARVD is lacking. The purpose of this systematic review was to better define the role of SAECG in ARVD.Methods:An extensive review of literature was done to specifically describe the prevalence of LP in ARVD and its determinants, explore the various options available to improve the diagnostic ability of SAECG, and provide recommendations for proper utilization of this technique.Results:LPs are frequent in ARVD (47–100%), and more prevalent in severe disease and in patients with documented spontaneous VT. SAECG is a useful test in following the characteristic evolutivity of the disease. 4–16% of normal family members of patients with ARVD also have abnormal SAECG results. Detection of LP in ARVD can be improved by employing a high‐pass filter of 25 Hz and specifically looking for changes in the Z leads.Conclusions:SAECG testing should be considered a standard part of the evaluation of patients with known or suspected ARVD. Further research is needed to confirm the value of SAECG testing in predicting arrhythmia risk and assessing the rate of disease progression, as well as to determine if greater prevalence of SAECG abnormalities in family members of patients with ARVD represents early detection of ARVD. The ongoing multidisciplinary study of right ventricular dysplasia will hopefully answer some of these questions.