STIMULATION AND STRYCHNINIZATION OF SUPRACALLOSAL ANTERIOR CINGULATE GYRUS
STIMULATION AND STRYCHNINIZATION OF SUPRACALLOSAL ANTERIOR CINGULATE GYRUS
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DOI：
10.1152/jn.1950.13.3.207
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发表时间：
1950-01-01
影响因子：
2.5
通讯作者：
LENNOX, MA
中科院分区：
文献类型：
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作者：
DUNSMORE, RH;LENNOX, MA
在猫和猴子身上，前扣带回被切断，放电的部位在解剖学上类似于抑制带区域。从猫脑向8秒、2秒、3秒和19秒的位置发射信号。除了其他人描述的那些区域外，只在猴子身上看到了向8发射信号。使用方波刺激器进行电刺激，频率为40次/秒，电压为2V，Sigma为10。这会产生不典型的运动、运动停止、呼吸停止和脑电改变。后者有4种类型。同侧大脑半球抑制士的宁棘波，同侧抑制睡眠(或拨号)纺锤波，双侧抑制自发性皮质活动，双侧和同侧均产生癫痫放电。这些影响都是相互独立地发生的，暗示着通过不同的途径进行调解。直接刺激尾状核不会消除士的宁刺突，但确实会消除一只动物的睡眠棘突。去掉尾状核阻止了睡眠纺锤波的进一步抑制。
In cats and monkeys, the anterior cingulate gyrus was strychninized and firing demonstrated to points anatomically similiar to the suppressor strip areas. Firing from the cat brain was to the presumed location of 8s, 2s, 3s, and 19s. Firing to 8s only was seen in the monkey in addition to those areas described by others. Electrical stimulation was done with a square wave stimulator using a frequency of 40/sec, 2 V. and a sigma of 10. This produced atypical motor movements, arrest of motor movements, arrest of respiration, and electroencephalographic changes. The latter were of 4 types. Strychnine spikes were suppressed from the ipsilateral hemisphere, sleep (or dial) spindles were suppressed on the ipsilateral side, spontaneous electrocortical activity was suppressed bilaterally and seizure discharges were produced bilaterally as well as ipsilaterally. These effects all occurred independantly of each other and suggested mediation by different pathways. Direct stimulation of the caudate nucleus did not eliminate strychnine spikes but did eliminate sleep spinules in one animal. Removal of the caudate nucleus prevented further supression of sleep spindles.