EndoCuff-assisted colonoscopy could improve adenoma detection rate: A meta-analysis of randomized controlled trials
EndoCuff-assisted colonoscopy could improve adenoma detection rate: A meta-analysis of randomized controlled trials
复制标题
EndoCuff 辅助结肠镜检查可提高腺瘤检出率：随机对照试验的荟萃分析
DOI：
10.1111/1751-2980.12814
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发表时间：
2019-10-22
影响因子：
3.5
通讯作者：
Zuo，Xiu Li
中科院分区：
文献类型：
--
作者：
Jian，Hai Xu;Feng，Bing Cheng;Zuo，Xiu Li
该Meta分析旨在评价与标准结肠镜检查（SC）相比，EndoCuff辅助结肠镜检查（EAC）是否可以提高腺瘤检出率（ADR）。方法检索PubMed、EMBASE、Scopus、科克伦图书馆和谷歌学术数据库中截至2019年3月发表的文章。纳入了所有比较EAC和SC组ADR的纯随机对照试验。合并二分数据以获得比值比和95%置信区间（CI），而使用平均差异和95% CI合并连续数据。Review Manager Version 5.3用于数据分析。Results 13个随机对照试验，包括9038例患者（EAC：4574; SC：4464）。EAC组的ADR显著优于SC组（比值比1.37，95% CI 1.15-1.62）。然而，有EAC和SC组之间的不良事件，盲肠插管率，盲肠插管time.ConclusionsEAC可以显着改善ADR，而不增加不良事件，特别是对操作员与低ADR无显着差异。此外，EAC和SC之间的盲肠插管时间和盲肠插管率无显著差异。
ObjectiveThis meta‐analysis aimed to evaluate whether EndoCuff‐assisted colonoscopy (EAC) could improve adenoma detection rate (ADR) compared with standard colonoscopy (SC).MethodsPubMed, EMBASE, Scopus, Cochrane Library, and Google Scholar databases were searched for articles published up to March 2019. All pure randomized controlled trials comparing ADR between EAC and SC groups were included. Dichotomous data were pooled to obtain the odds ratio with a 95% confidence interval (CI), whereas continuous data were pooled using a mean difference with 95% CI. Review Manager Version 5.3 was used for data analysis.ResultsThirteen randomized controlled trials consisting of 9038 patients (EAC: 4574; SC: 4464) were included. The EAC group showed significant superiority over the SC group in ADR (odds ratio 1.37, 95% CI 1.15–1.62). However, there were no differences between the EAC and SC groups in adverse events, cecal intubation rate, and cecal intubation time.ConclusionsEAC could significantly improve ADR without increasing adverse events, especially for operators with low ADRs. In addition, no significant difference was observed in cecal intubation time and cecal intubation rate between EAC and SC.