The impacts of migraine on functioning: Results from two qualitative studies of people living with migraine.
The impacts of migraine on functioning: Results from two qualitative studies of people living with migraine.
复制标题
偏头痛对功能的影响：对偏头痛患者进行的两项定性研究的结果。
作者：
Mangrum,Rikki;Bryant,AlexandraL;Gerstein,MayaT;McCarrier,KellyP;Houts,CarrieR;McGinley,JamesS;Buse,DawnC;Lipton,RichardB;Wirth,RJ
目的通过全面的数据收集、分析，为了解偏头痛患者对生活的看法而进行的定性研究往往集中在狭窄的主题或特定的患者群体上，或者有选择地报道。临床结局评估系统（MiCOAS）项目，这是一项FDA资助的项目，旨在为偏头痛临床试验开发一套以患者为中心的核心结局指标。参与者自我报告被医疗保健专业人员诊断为偏头痛，并参加了关于他们对偏头痛症状和影响的经历的半结构化定性访谈。面试成绩单进行编码，以确定和定义的概念，然后被分组为广泛的领域的基础上的概念similarity.ResultsA共66个概念被确定：12个身体功能，16个认知功能，10个社会角色功能，19个情绪和心理功能，和9个偏头痛管理。参与者描述了偏头痛发作症状和对功能的影响之间复杂而多样的关系。偏头痛的影响进一步受到许多背景因素的影响，如人们的个人社会环境和日常需求的水平，他们面临的功能。ConclusionFindings表明，偏头痛影响个人功能的多种方式和这些影响的性质是依赖于社会背景因素。这些结果正在用于开发核心措施，旨在提高我们对偏头痛负担和偏头痛治疗疗效的理解。研究结果还提供了新的见解，并提出了有关偏头痛经验的新问题，可用于指导未来的研究。
ObjectiveTo describe the impact of migraine on functioning based on comprehensive data collection, analysis, and reporting of patients' experiences.BackgroundQualitative research conducted to understand patients' perspectives on living with migraine has often focused on narrow topics or specific groups of patients or has been selectively reported.MethodsQualitative interviews with 71 participants were conducted during two concept elicitation studies as part of the Migraine Clinical Outcome Assessment System (MiCOAS) project, an FDA grant‐funded program designed to develop a core set of patient‐centered outcome measures for migraine clinical trials. Participants self‐reported being diagnosed with migraine by a healthcare professional and participated in semi‐structured qualitative interviews about their experiences with the symptoms and impacts of migraine. Interview transcripts were coded to identify and define concepts, which were then grouped into broad domains based on conceptual similarities.ResultsA total of 66 concepts were identified: 12 for physical functioning, 16 for cognitive functioning, 10 for social role functioning, 19 for emotional and psychological functioning, and 9 related to migraine management. Participants described a complex and varied relationship between migraine attack symptoms and impacts on functioning. Impacts from migraine were further influenced by numerous contextual factors, such as people's individual social environments and the level of day‐to‐day demand for functioning they face.ConclusionFindings showed that migraine impacted individual functioning in multiple ways and the nature of these impacts was dependent on social‐contextual factors. The results are being used in the development of core measures designed to improve our understanding of the burden of migraine and the efficacy of migraine therapies. The results also offer new insights and raise new questions about migraine experience that can be used to guide future research.