Evaluation of the efficacy of triamcinolone acetonide in the treatment of keloids by high-frequency ultrasound
Evaluation of the efficacy of triamcinolone acetonide in the treatment of keloids by high-frequency ultrasound
复制标题
高频超声评价曲安奈德治疗瘢痕疙瘩的疗效
DOI：
10.1111/srt.12820
复制
发表时间：
2020
影响因子：
2.2
通讯作者：
Li Zhiming
中科院分区：
文献类型：
--
作者：
Cai Lei;Hu Murong;Lin Lele;Zheng Tianyin;Liu Jingjing;Li Zhiming
BackgroundIntralesional injection of triamcinolone acetonide is an effective method for treating keloids. It still lacks effective and objective evaluation methods. This study aimed to observe the efficacy of intralesional triamcinolone acetonide injections for the treatment of keloids and to explore the role of high‐frequency ultrasound in the monitoring and evaluation of keloids therapy.MethodsFifty‐one patients with keloids were treated with triamcinolone acetonide, once a week for 4 weeks. Lesions were detected, recorded, and evaluated using digital photography and high‐frequency ultrasound before and after treatment.ResultsHigh‐frequency ultrasound showed the depth of drug injection. After the last treatment, an average decrease in dermal tissue layer thickness of 39.0% is compared with before treatment. In addition, there are significant differences in the effectiveness of clinical assessments and ultrasound assessments of keloids with or without subjective symptoms.ConclusionThe observed results confirmed that intralesional injections of triamcinolone acetonide can effectively treat keloids. High‐frequency ultrasound can be used as a therapeutic monitoring and therapeutic evaluation tool for intralesional injections of triamcinolone acetonide.
