Validating the absolute reliability of a fat free mass estimated equation in hemodialysis patients using Near-Infrared Spectroscopy
Validating the absolute reliability of a fat free mass estimated equation in hemodialysis patients using Near-Infrared Spectroscopy
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使用近红外光谱验证血液透析患者去脂质量估计方程的绝对可靠性
DOI：
10.1111/1744-9987.12283
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发表时间：
2015
期刊：
影响因子：
1.9
通讯作者：
Takashi Sato
中科院分区：
文献类型：
--
作者：
Kenichi Kono;Yusuke Nishida;Yoshihumi Moriyama;Masahiro Taoka;Takashi Sato
用近红外光谱(NIRS)测量的脱脂质量(FFM)来评估营养状态在临床上是有用的。这一测量应包括患者透析后的体重(“干重”)，以排除水质量的任何变化的影响。因此，我们使用近红外光谱来研究干重FFM的回归、自变量和绝对可靠性。这项研究包括47名来自血液透析单元的门诊患者。在透析前测量体重，在透析治疗前后用近红外光谱测量FFM。以干重为因变量，采用多元回归分析方法估计FFM。透析前测得的FFM(MW-FFM)、测得的体重与干体重的差值(MW-DW)是自变量。我们进行了Bland-Altman分析，以检测透析治疗后统计估计的FFM和测量的FFM之间的误差。估测干重的多元回归方程为：Dw‐FFM = 0.038 + (0.984 × Mw‐FFM) + (−0.571 × [Mw‐Dw])；R2= 0.99)。FFM干重的估计值和实测值之间没有系统性偏差。利用近红外光谱技术，干重中的FFM可以通过包含测量重量中的FFM和测量重量与干重之间的差的公式来计算。
The assessment of nutritional states using fat free mass (FFM) measured with near‐infrared spectroscopy (NIRS) is clinically useful. This measurement should incorporate the patient's post‐dialysis weight (“dry weight”), in order to exclude the effects of any change in water mass. We therefore used NIRS to investigate the regression, independent variables, and absolute reliability of FFM in dry weight. The study included 47 outpatients from the hemodialysis unit. Body weight was measured before dialysis, and FFM was measured using NIRS before and after dialysis treatment. Multiple regression analysis was used to estimate the FFM in dry weight as the dependent variable. The measured FFM before dialysis treatment (Mw‐FFM), and the difference between measured and dry weight (Mw‐Dw) were independent variables. We performed Bland‐Altman analysis to detect errors between the statistically estimated FFM and the measured FFM after dialysis treatment. The multiple regression equation to estimate the FFM in dry weight was: Dw‐FFM = 0.038 + (0.984 × Mw‐FFM) + (−0.571 × [Mw‐Dw]); R2= 0.99). There was no systematic bias between the estimated and the measured values of FFM in dry weight. Using NIRS, FFM in dry weight can be calculated by an equation including FFM in measured weight and the difference between the measured weight and the dry weight.