Detailed ECG Analysis of Atrial Repolarization in Humans
Detailed ECG Analysis of Atrial Repolarization in Humans
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DOI：
10.1111/j.1542-474x.2008.00268.x
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发表时间：
2009-01-01
影响因子：
1.9
通讯作者：
Platonov, Pyotr G.
中科院分区：
文献类型：
--
作者：
Holmqvist, Fredrik;Carlson, Jonas;Platonov, Pyotr G.
引言：由于QRS波群通常会掩盖其ECG迹线，因此有关人类心房复极的数据很少。在本研究中，连续三度房室传导阻滞患者进行了研究，以更好地描述人类Ta wave.Methods和结果：40例患者（平均年龄75岁，17名男性）。心电图记录前停用所有抗心律失常药物。记录标准12导联ECG，转换为正交导联，并使用信号平均P波分析进行研究。平均P波持续时间为124 ± 16 ms。PTa持续时间为449 ± 55 ms（校正后PTa为512 ± 60 ms），Ta持续时间（P波末端至Ta波末端）为323 ± 56 ms。所有导联Ta波的极性与P波相反。Ta峰值位于导联Y的196 +/- 55 ms、导联X的216 +/- 50 ms和导联Z的335 +/- 92 ms。P波时限与Ta时限、Ta峰振幅与Ta时限无相关性。结论：Ta波具有相反的极性，持续时间通常是P波的两到三倍。虽然Ta峰偶尔可能位于正常AV传导期间的PQ间期，但从该段分析中不太可能获得足够的信息来区分正常和异常心房复极。因此，需要一种用于窦性心律期间的Q波消除的算法以进一步改进分析。Ann Noninvasive Electrocardiol 2009;14（1）：13-18。
Introduction: Data on human atrial repolarization are scarce since the QRS complex normally obscures its ECG trace. In the present study, consecutive patients with third-degree AV block were studied to better describe the human Ta wave.Methods and Results: Forty patients (mean age 75 years, 17 men) were included. All anti-arrhythmic drugs were discontinued before ECG recording. Standard 12-lead ECGs were recorded, transformed to orthogonal leads and studied using signal-averaged P wave analysis. The average P wave duration was 124 +/- 16 ms. The PTa duration was 449 +/- 55 ms (corrected PTa 512 +/- 60 ms) and the Ta duration (P wave end to Ta wave end) was 323 +/- 56 ms. The polarity of the Ta wave was opposite to that of the P wave in all leads. The Ta peaks were located at 196 +/- 55 ms in Lead Y, 216 +/- 50 ms in Lead X, and 335 +/- 92 in Lead Z. No correlation was found between P wave duration and Ta duration, or between Ta peak amplitude and Ta duration. The morphology of the Ta wave was similar regardless of the interatrial conduction.Conclusions: The Ta wave has the opposite polarity, and the duration is generally two to three times that, of the P wave. Although the Ta peak may occasionally be located in the PQ interval during normal AV conduction, it is unlikely that enough information can be obtained from analysis of this segment to differentiate normal from abnormal atrial repolarization. Hence, an algorithm for QRST cancellation during sinus rhythm is needed to further improve analysis.Ann Noninvasive Electrocardiol 2009;14(1):13-18.