Using e-technologies in clinical trials
Using e-technologies in clinical trials
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DOI：
10.1016/j.cct.2015.07.007
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发表时间：
2015-11-01
影响因子：
2.2
通讯作者：
Winstanley, Erin L.
中科院分区：
文献类型：
--
作者：
Rosa, Carmen;Campbell, Aimee N. C.;Winstanley, Erin L.
临床试验在将电子技术（利用移动的设备或互联网的数字和电子技术）纳入研究的设计和执行方面进展缓慢。与此同时，个人和企业越来越依赖电子平台，大多数人已将此类技术融入日常生活。本文概述了电子技术在临床试验研究中的应用，特别是在过去的十年中，以移动的和基于互联网的工具的快速增长为标志。提供了在数据收集、招募和保留、提供干预措施和传播方面使用电子技术的好处和挑战，以及对电子技术在临床试验研究中的监管监督现状的描述。作为电子技术可用于提供干预措施的方式的一个例子，介绍了用于治疗药物使用障碍的电子技术概要。使用电子技术设计和实施临床试验有可能接触到广泛的受众，使试验更有效，同时也降低了成本;然而，考虑到使用新技术的许多挑战以及对参与者隐私/保密性的威胁，研究人员在采用这些工具时应谨慎。使用电子技术的挑战可以通过仔细的规划、有益的伙伴关系和深谋远虑来克服。基于网络和智能手机的应用程序的作用正在扩大，科学家和公众越来越多地使用这些平台，使它们成为不可忽视的工具。爱思唯尔公司出版
Clinical trials have been slow to incorporate e-technology (digital and electronic technology that utilizes mobile devices or the Internet) into the design and execution of studies. In the meantime, individuals and corporations are relying more on electronic platforms and most have incorporated such technology into their daily lives. This paper provides a general overview of the use of e-technologies in clinical trials research, specifically within the last decade, marked by rapid growth of mobile and Internet-based tools. Benefits of and challenges to the use of e-technologies in data collection, recruitment and retention, delivery of interventions, and dissemination are provided, as well as a description of the current status of regulatory oversight of e-technologies in clinical trials research. As an example of ways in which e-technologies can be used for intervention delivery, a summary of e-technologies for treatment of substance use disorders is presented. Using e-technologies to design and implement clinical trials has the potential to reach a wide audience, making trials more efficient while also reducing costs; however, researchers should be cautious when adopting these tools given the many challenges in using new technologies, as well as threats to participant privacy/confidentiality. Challenges of using e-technologies can be overcome with careful planning, useful partnerships, and forethought. The role of web- and smartphone-based applications is expanding, and the increasing use of those platforms by scientists and the public alike make them tools that cannot be ignored. Published by Elsevier Inc.