Cerebrospinal fluid dynamics and relation with blood flow -: A magnetic resonance study with semiautomated cerebrospinal fluid segmentation
Cerebrospinal fluid dynamics and relation with blood flow -: A magnetic resonance study with semiautomated cerebrospinal fluid segmentation
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DOI：
10.1097/00004424-200107000-00003
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发表时间：
2001-07-01
影响因子：
6.7
通讯作者：
Idy-Peretti, I
中科院分区：
文献类型：
--
作者：
Balédent, O;Henry-Feugeas, MCC;Idy-Peretti, I
理由和目标。研究和测量血液和脑脊液 (CSF) 流量波形关系的时间和幅度方面。方法。使用电影相位对比磁共振成像脉冲序列来测量 16 名年龄 27 +/- 4 岁的健康受试者的血液和脑脊液流量。开发了一种半自动分割算法来研究脑脊液流。结果。由 5 名观察者进行的导水管测量和宫颈测量的标准偏差分别为 1% 和 4%。动脉收缩期峰值为 1087 +/- 169 mL/min，颈部脑脊液冲洗峰值 (173 +/- 59 mL/min) 发生在颈内动脉收缩期峰值之后的心动周期的 5% +/- 3% 处。导水管冲洗流量峰值 (13 +/- 5 mL/min) 出现在颈内动脉收缩峰值之后心动周期的 21% +/- 7% 处。结论。 CSF 分割算法是可重复的。脑部扩张很快受到主要的脑外脑脊液冲洗流的调节，而脑室脑脊液仅做出很小的贡献。
RATIONALE AND OBJECTIVES. TO investigate and measure temporal and amplitude aspects of blood and cerebrospinal fluid (CSF) flow waveform relations.METHODS. A cine phase-contrast magnetic resonance imaging pulse sequence was used to measure blood and CSF flow in 16 healthy subjects aged 27 +/- 4 years. A semiautomated segmentation algorithm was developed to study CSF flow.RESULTS. Standard deviations of the aqueductal and cervical how measurements carried out by five observers were 1% and 4%, respectively. The peak systolic arterial dow was 1087 +/- 169 mL/min, and the peak cervical CSF flush (173 +/- 59 mL/min) occurred at 5% +/- 3% of the cardiac cycle after the internal carotid systolic peak how. Peak aqueductal flush flow (13 +/- 5 mL/min) occurred at 21% +/- 7% of the cardiac cycle after the internal carotid systolic peak how.CONCLUSIONS. The CSF segmentation algorithm is reproducible. Brain expansion was quickly regulated by a major extracerebral CSF flush flow, whereas ventricular CSF made only a very small contribution.