Magnetic resonance imaging in pseudotumor cerebri
Magnetic resonance imaging in pseudotumor cerebri
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DOI：
10.1016/s0161-6420(98)99039-x
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发表时间：
1998-09-01
期刊：
影响因子：
13.7
通讯作者：
Vaphiades, M
中科院分区：
文献类型：
--
作者：
Brodsky, MC;Vaphiades, M
目的：目的：探讨磁共振成像（MR）是否可用于预测颅内压升高的存在。设计：回顾性病例系列。参与者：20例假性脑瘤患者和20例对照组。干预：磁共振成像。主要结果：测量以下6种神经影像学体征的存在或不存在：（1）后巩膜扁平;（2）板前视神经强化;（3）视神经周围蛛网膜下腔扩张;（4）板前视神经眼内突出;（5）眶视神经垂直弯曲;（6）空蝶鞍。MRI显示80%的假性脑瘤患者后巩膜扁平，70%的患者空蝶鞍，45%的患者视神经周围蛛网膜下腔扩张，视神经板前强化占50%，眶视神经垂直弯曲占40%，板前视神经眼内突出占30%。每一个神经影像学迹象中检测到5%的对照组，除了增强层前视神经，这是没有检测到对照组。基于这些磁共振成像的迹象，考官是能够预测的存在下，颅内压升高的90%的情况下，与pseudotumor cerebri和所有控制subjects.Conclusions的情况下，颅内压升高产生一个星座的磁共振成像的迹象，可以帮助建立pseudotumor cerebri的诊断。
Objective: To determine whether magnetic resonance (MR) imaging can be used to predict the presence of elevated intracranial pressure.Design: Retrospective case series.Participants: Twenty patients with pseudotumor cerebri and 20 control subjects.Intervention: Magnetic resonance imaging.Main Outcome Measures: The presence or absence of the following six neuroimaging signs was measured, (1) flattening of the posterior sclera; (2) enhancement of the prelaminar optic nerve; (3) distension of the perioptic subarachnoid space; (4) intraocular protrusion of the prelaminar optic nerve; (5) vertical tortuosity of the orbital optic nerve, and (6) empty sella.Results: The MR imaging disclosed flattening of the posterior sclera in 80% of patients with pseudotumor cerebri, empty sella in 70%, distension of the perioptic subarachnoid space in 45%, enhancement of the prelaminar optic nerve in 50%, vertical tortuosity of the orbital optic nerve in 40%, and intraocular protrusion of the prelaminar optic nerve in 30%. Each neuroimaging sign was detected in 5% of control subjects, except for enhancement of the prelaminar optic nerve, which was not detected in control subjects. Based on these MR imaging signs, the examiner was able to predict the presence of elevated intracranial pressure in 90% of cases with pseudotumor cerebri and the absence of elevated intracranial pressure in all control subjects.Conclusions: Elevated intracranial pressure produces a constellation of MR imaging signs that can assist in establishing the diagnosis of pseudotumor cerebri.