FUNCTIONAL ADAPTATION OF BONE TO INCREASED STRESS - EXPERIMENTAL-STUDY
FUNCTIONAL ADAPTATION OF BONE TO INCREASED STRESS - EXPERIMENTAL-STUDY
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DOI：
10.2106/00004623-197961040-00008
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发表时间：
1979-01-01
影响因子：
5.3
通讯作者：
MCFIE, H
中科院分区：
文献类型：
--
作者：
GOODSHIP, AE;LANYON, LE;MCFIE, H
在正常行走的小猪中，记录主压缩应变（ε 2），如通过连接到桡骨轴的应变计所显示的。正常动物3个月内的平均主压缩应变与年龄或体重之间无相关性。直接在单侧去除尺骨骨干后，桡骨干上的主压缩应变增加了2-2 1/2倍。正常值。尺骨截骨术引起的桡骨应变水平增加导致桡骨快速而实质性的重塑反应。尺骨截骨术后3个月，过度应变桡骨骨膜周长所包围的骨面积接近对侧肢体桡骨和尺骨的值，桡骨中段骨组织的横截面积也接近对侧肢体桡骨和尺骨的值。单侧截骨术后3个月左右桡骨的主压应变无明显差异，接近正常值。
In young pigs walking normally, the principal compressive strains (.epsilon.2) were recorded as revealed by strain gauges attached to the shaft of the radius. No correlation between the mean principal compressive strain and either age or wt in normal animals over the 3 mo. time span of the experiment was found. Directly after unilateral removal of the ulnar diaphysis, the principal compressive strain on the radial shaft increased by 2-2 1/2 .times. its normal value. The increased level of strain in the radius caused by ulnar ostectomy resulted in a rapid and substantial remodeling response in the radius. Months (3) after ulnar ostectomy, the area of bone enclosed by the periosteal perimeter of the overstrained radius approached the value for the radius and ulna together in the contralateral limb, as did the cross-sectional area of the bone tissue in the mid-shaft of that radius. Months (3) after unilateral ostectomy, the principal compressive strain was not significantly different in the left and right radii and approached normal values.