Elevated preoperative neutrophil-to-lymphocyte ratio predicts early adverse outcomes in uncomplicated type B aortic dissection undergoing TEVAR.
Elevated preoperative neutrophil-to-lymphocyte ratio predicts early adverse outcomes in uncomplicated type B aortic dissection undergoing TEVAR.
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DOI：
10.1186/s12872-021-01904-y
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发表时间：
2021-02-16
影响因子：
2.1
通讯作者：
Jing Z
中科院分区：
文献类型：
--
作者：
Zhu H;Zhang L;Liang T;Li Y;Zhou J;Jing Z
单纯性 B 型主动脉夹层 (uTBAD) 的胸主动脉腔内修复术 (TEVAR) 具有良好的长期结果，但与最佳治疗相比，早期不良事件较多。最近，有关血管手术的临床证据表明，术前全身炎症反应升高预示着不良临床事件。我们研究的目的是评估接受 TEVAR 的 uTBAD 患者术前中性粒细胞与淋巴细胞比率 (NLR) 和早期结果之间的关系。 这项回顾性研究纳入了 2015 年 1 月至 2018 年 12 月期间诊断为 uTBAD 的 216 名患者。中位随访期 (IQR) 为 21 (15-33) 个月。早期不良事件定义为手术后 2 年内发生。患者中位年龄为 60（IQR，48-68）岁，78.7% 为男性。 24 名患者（11.1%）发生了早期不良事件。在多变量分析中，术前 NLR（HR/SD，1.98；95 % CI，1.14–3.44；P = 0.015）与 2 年不良事件相关。 NLR 是接受 TEVAR 的 uTBAD 患者早期不良事件的独立预测因素。
Thoracic aortic endovascular repair (TEVAR) of uncomplicated type B aortic dissection (uTBAD) has favorable long-term outcomes but higher early adverse events compared with the optimal medical treatment. Recently, clinical evidence concerning vascular surgery indicates that elevated preoperative systemic inflammatory response predicts adverse clinical events. The aim of our study was to evaluate the relationship between preoperative neutrophil-to-lymphocyte ratio (NLR) and early outcomes of uTBAD patients undergoing TEVAR. 216 patients diagnosed with uTBAD were included in this retrospective study between January 2015 and December 2018. The median (IQR) follow-up period was 21 (15–33) months. An early adverse event was defined as occurring within 2 years after the procedure. Median patient age was 60 (IQR, 48–68) years and 78.7 % were male. Early adverse events occurred in 24 patients (11.1 %). In the multivariable analysis, preoperative NLR (HR per SD, 1.98; 95 % CI, 1.14–3.44; P = 0.015) was associated with 2-year adverse events. NLR is an independent predictive factor of early adverse events in uTBAD patients undergoing TEVAR.
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影响因子：
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作者：
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通讯作者：
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影响因子：
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影响因子：
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作者：
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DOI：
10.1161/circinterventions.113.000463
发表时间：
2013-08-01
影响因子：
5.6
作者：
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