Impact of a standardized hand hygiene program on the incidence of nosocomial infection in very low birth weight infants
Impact of a standardized hand hygiene program on the incidence of nosocomial infection in very low birth weight infants
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DOI：
10.1016/j.ajic.2007.10.018
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发表时间：
2008-08-01
影响因子：
4.9
通讯作者：
Faldella, Giacomo
中科院分区：
文献类型：
--
作者：
Capretti, Maria Grazia;Sandri, Fabrizio;Faldella, Giacomo
背景资料：本研究旨在探讨标准化手卫生程序对新生儿重症监护室（NICU）收治的极低出生体重儿（VLBW）（出生体重< 1500 g）医院感染（NI）率的影响。在第一阶段，鼓励工作人员使用普通液体洗涤剂（0.5%三氯生）洗手。在第二个时期，一个标准化的手卫生程序实施使用抗菌肥皂（4%葡萄糖酸氯己定）和酒精为基础的手rubs.Results：NI后72小时的生活中检测到16的85 VLBW婴儿在第一个时期和5的80 VLBW婴儿在第二个时期。中心静脉导管定植率在第二阶段（5.8%）明显低于第一阶段（16.6%）。结论：在我们的新生儿重症监护室，NI的发生率在VLBW婴儿引入标准化洗手协议后显着降低。根据我们的经验，适当的手部卫生计划每年可以节省大约10次NI发作，每次发作的成本为10，000美元。因此，改善手部卫生习惯是NICU中一项具有成本效益的计划。
Background: This study examined the effects of a standardized hand hygiene program on the rate of nosocomial infection (NI) in very low birth weight (VLBW) infants (birth weight < 1500 g) admitted to our neonatal intensive care unit (NICU).Methods: We compared the rate of NI in VLBW infants in 2 separate periods. In the first period, staff were encouraged to perform handwashing using a plain fluid detergent (0.5% triclosan). In the second period, a standardized hand hygiene program was implemented using antimicrobial soap (4% chlorhexidine gluconate) and alcohol-based hand rubs.Results: NI after 72 hours of life was detected in 16 of the 85 VLBW infants in the first period and in 5 of the 80 VLBW infants in the second period. The rate of central venous catheter colonization was significantly lower in the second period (5.8%) than in the first period (16.6%).Conclusion: In our NICU, the incidence of NI in VLBW infants was significantly reduced after the introduction of a standardized handwashing protocol. In our experience, a proper hand hygiene program can save approximately 10 NI episodes/year, at a cost of $10,000 per episode. Therefore, improving hand hygiene practice is a cost-effective program in the NICU.