Molecular mass estimation by PFG NMR spectroscopy
Molecular mass estimation by PFG NMR spectroscopy
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DOI：
10.1016/j.jmr.2006.12.004
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发表时间：
2007-03-01
影响因子：
2.2
通讯作者：
Harris, Douglas J.
中科院分区：
文献类型：
--
作者：
Crutchfield, Christopher A.;Harris, Douglas J.
发展了一种简化的PFG NMR扩散分析方法，用于估算小分子在稀水溶液和有机溶液中的分子量。利用内部参考来提高实验稳健性并简化数据分析。具体地，分别选择四甲基硅烷（TMS）和HDO用于有机和水性参比分子。相对扩散性分子质量的相关性经验开发的范围为2-1280克/摩尔的稀CDCl 3和D2 O的解决方案。发现预测分子量的中位误差为10 rel%。通过分析橄榄油中的主成分和次成分，证明了该方法的实用性。(c)2006年爱思唯尔公司All rights reserved.
A simplified PFG NMR diffusion analysis method was developed to estimate the molecular mass of small molecules in dilute aqueous and organic solutions. Internal referencing was utilized to improve the experimental robustness and simplify the data analysis. Specifically, tetramethylsilane (TMS) and HDO were chosen for the organic and aqueous reference molecules, respectively. Relative diffusivity-molecular mass correlations were empirically developed in the range of 2-1280 g/mol for dilute CDCl3 and D2O solutions. The median error in the predicted molecular mass was found to be 10 rel%. The utility of the method was demonstrated by analyzing the major and minor components in olive oil. (c) 2006 Elsevier Inc. All rights reserved.