The potential demand for an AIDS vaccine in Thailand
The potential demand for an AIDS vaccine in Thailand
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DOI：
10.1016/s0168-8510(01)00119-1
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发表时间：
2001-08-01
期刊：
影响因子：
3.3
通讯作者：
Suraratdecha, C
中科院分区：
文献类型：
--
作者：
Tangcharoensathien, V;Phoolcharoen, W;Suraratdecha, C
最近在泰国进行的预防性疫苗第三阶段临床试验促使人们研究公众、雇主和家庭对疫苗的潜在需求。本研究的目的是展示艾滋病毒/艾滋病的影响，估计艾滋病疫苗的预算需要和设计不同人群的疫苗接种策略。该分析是基于现有的二手数据和关于不同风险群体继发感染水平的若干假设。在15个群体中，我们确定了8个群体为潜在的疫苗接种者：直接CSW，治疗中的IDU，治疗外的IDU，男性STD，运输工人，CSW间接。士兵和囚犯。疫苗预算（不包括其他运营支出）是根据单剂量方案估算的，每剂100泰铢（3美元）至1000泰铢（29美元）。未受感染的追赶人口总共需要180 - 1770万美元，随后一年的维持人口需要20 - 190万美元。我们预见艾滋病疫苗的消费将相对低效和不公平。这需要适当的政策分析和政府干预。在采用疫苗之前，必须采取强有力的预防措施。艾滋病疫苗可以发挥补充作用，而不是替代作用。透彻理解、与利益攸关方进行广泛协商和公开辩论是制定健全政策的关键步骤。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
The recent ongoing phase III clinical trial of a preventive vaccine in Thailand has prompted studies on potential demand for the vaccine among public, employers and households. This study aims to demonstrate the impact of HIV/AIDS, estimate the AIDS vaccine budget required and design the vaccination strategies for different population groups. The analysis is based on available secondary data and several assumptions on levels of secondary infections among various risk groups. Among 15 groups, we identified eight groups as potential vaccinees: Direct CSW, IDU in treatment, IDU out of treatment, male STD, transport workers, CSW indirect. conscripts and prisoners. The vaccine budget, excluding other operating expenditure, was estimated based on a single dose regimen ranging from 100 Baht (US$3) to 1000 Baht (US$29) per dose. A total of US$1.8-17.7 million is required for non-infected catch-up population and US$0.2-1.9 million for the maintenance population in the subsequent year. We foresee a relative inefficient and inequitable consumption of AIDS vaccine. which requires proper policy analysis and government interventions. Before vaccine adoption, strong preventive measures must be in place. AIDS vaccine could play an additional, not a substituting, role. A thorough understanding, a wide consultation with stakeholders and public debates are crucial steps for sound policy formulation. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.