Understanding epigenomics based on the rice model
Understanding epigenomics based on the rice model
复制标题
基于水稻模型理解表观基因组学
DOI：
10.1007/s00122-019-03518-7
复制
发表时间：
2020
影响因子：
5.4
通讯作者：
Yu Zhao
中科院分区：
文献类型：
--
作者：
Yue Lu;Dao-Xiu Zhou;Yu Zhao
本文综述了水稻表观基因组学的最新研究进展，包括DNA甲基化、组蛋白修饰、非编码RNA和三维基因组学。摘要水稻作为表观基因组研究的模式植物，使植物表观遗传学的研究取得了很大进展。水稻表观基因组图谱和三维染色质结构的研究揭示了水稻发育和适应环境变化过程中基因调控的特征和意义。水稻染色质调节子功能的研究结果揭示了植物表观基因组信息的建立、识别和重置机制。与重要农艺性状相关的几个水稻表观等位基因的克隆突出了表观基因组变异在水稻植物生长、适合度和产量中的重要性。本文对水稻表观基因组学的研究进展进行了总结和分析，并讨论了该领域未来研究的挑战和方向。
Key messageThe purpose of this paper provides a comprehensive overview of the recent researches on rice epigenomics, including DNA methylation, histone modifications, noncoding RNAs, and three-dimensional genomics. The challenges and perspectives for future research in rice are discussed.AbstractRice as a model plant for epigenomic studies has much progressed current understanding of epigenetics in plants. Recent results on rice epigenome profiling and three-dimensional chromatin structure studies reveal specific features and implication in gene regulation during rice plant development and adaptation to environmental changes. Results on rice chromatin regulator functions shed light on mechanisms of establishment, recognition, and resetting of epigenomic information in plants. Cloning of several rice epialleles associated with important agronomic traits highlights importance of epigenomic variation in rice plant growth, fitness, and yield. In this review, we summarize and analyze recent advances in rice epigenomics and discuss challenges and directions for future research in the field.