Near-Infrared Luminescence Sensing of Glutamic Acid, Aspartic Acid, and Their Dipeptides with Tris(β-diketonato)lanthanide Probes†
Near-Infrared Luminescence Sensing of Glutamic Acid, Aspartic Acid, and Their Dipeptides with Tris(β-diketonato)lanthanide Probes†
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DOI：
10.1002/hlca.200900112
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发表时间：
2009-11
影响因子：
1.8
通讯作者：
H. Tsukube;K. Yano;S. Shinoda
中科院分区：
文献类型：
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作者：
H. Tsukube;K. Yano;S. Shinoda
一系列具有Yb3+， Eu3+和Nd3+中心的三（β-二酮酸）镧系元素被表征为针对谷氨酸，天冬氨酸及其二肽的发光传感探针，这些二肽是神经系统，味觉受体和其他生物系统的重要底物。特别是，三（6,6,7,7,8,8,8-七氟-2,2-二甲基辛烷-3,5-二氮杂）镱（III）对这些生物底物的响应表现出约980 nm的近红外发射。与普通发光探针相比，近红外发射复合物具有几个优点；因此，所提出的镧系配合物在蛋白质组学、代谢学、食品科学、天体生物学和相关技术方面具有潜在的分析应用前景。
A series of tris(β-diketonato)lanthanides with Yb3+, Eu3+, and Nd3+ centers were characterized as luminescent sensing probes specific to glutamic acid, aspartic acid, and their dipeptides, which are important substrates involved in nervous systems, taste receptors, and other biological systems. In particular, tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyloctane-3,5-dionato)ytterbium(III) exhibited a near-infrared emission around 980 nm in response to these biological substrates. Near-infrared-emissive complexes have several advantages over common luminescent probes; therefore, the proposed lanthanide complexes have potential analytical applications in proteomics, metabolics, food science, astrobiology, and related technologies.