Subclinical Legionella infection in workers near the source of a large outbreak of legionnaires disease
Subclinical Legionella infection in workers near the source of a large outbreak of legionnaires disease
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DOI：
10.1086/322049
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发表时间：
2001-08-15
影响因子：
6.4
通讯作者：
Conyn-van Spaendonck, MAE
中科院分区：
文献类型：
--
作者：
Boshuizen, HC;Neppelenbroek, SE;Conyn-van Spaendonck, MAE
对1999年花卉贸易展的参展商进行了一项调查，其中展出的漩涡温泉引起了军团病（LD）的大爆发。共有742名没有退伍军人症的参展商交回问卷，询问他们在展览会期间的行踪及展览会后的健康情况，并提供血液样本，以检测抗退伍军人症的IgM及IgG抗体。参展商的平均抗体水平高于一般人群。越是靠近漩涡的参展商，他们的抗体水平就越高。高正常值和高滴度水平在接触较多的工人中更常见，这表明在可能接触的受试者中进行血清调查是暴发调查的一个有价值的工具。根据工作地点的估计，在接触较多和接触较少的群体之间观察到健康投诉的一些差异，但在不同抗体水平的群体之间发现的差异很少。
A survey was conducted of exhibitors at a 1999 floral trade show, where a whirlpool spa on display caused a large outbreak of legionnaires disease (LD). In total, 742 exhibitors without LD returned a questionnaire on their whereabouts during the fair and their health afterward and supplied blood samples for the detection of IgM and IgG antibodies against Legionella pneumophila. The exhibitors had higher average antibody levels than did the general population. The closer to the whirlpool that the exhibitors worked, the higher their antibody levels. Both high-normal and high titer levels were found more frequently among workers with more exposure, suggesting that serosurveys among potentially exposed subjects are a valuable tool for outbreak investigation. Some differences in health complaints were observed between the more and less exposed groups, as estimated by the workplace location, but few differences were found between groups with different antibody levels.