Change in spontaneous baroreflex control of pulse interval during heat stress in humans.
Change in spontaneous baroreflex control of pulse interval during heat stress in humans.
复制标题
人类热应激期间自发压力反射控制脉搏间隔的变化。
DOI：
10.1152/japplphysiol.01019.2001
复制
发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Mack,GaryW
中科院分区：
文献类型：
--
作者：
Lee,Kichang;Jackson,DwayneN;Cordero,DouglasL;Nishiyasu,Takeshi;Peters,JochenK;Mack,GaryW
Spontaneous baroreflex control of pulse interval (PI) was assessed in healthy volunteers under thermoneutral and heat stress conditions. Subjects rested in the supine position with their lower legs in a water bath at 34°C. Heat stress was imposed by increasing the bath temperature to 44°C. Arterial blood pressure (Finapres), PI (ECG), esophageal and skin temperature, and stroke volume were continuously collected during each 5-min experimental stage. Spontaneous baroreflex function was evaluated by multiple techniques, including1) the mean slope of the linear relationship between PI and systolic blood pressure (SBP) with three or more simultaneous increasing or decreasing sequences,2) the linear relationship between changes in PI and SBP (ΔPI/ΔSBP) derived by using the first differential equation,3) the linear relationship between changes in PI and SBP with simultaneously increasing or decreasing sequences (+ΔPI/+ΔSBP or -ΔPI/-ΔSBP), and4) transfer function analysis. Heat stress increased esophageal temperature by 0.6 ± 0.1°C, decreased PI from 1,007 ± 43 to 776 ± 37 ms and stroke volume by 16 ± 5 ml/beat. Heat stress reduced baroreflex sensitivity but increased the incidence of baroreflex slopes from 5.2 ± 0.8 to 8.6 ± 0.9 sequences per 100 heartbeats. Baroreflex sensitivity was significantly correlated with PI or vagal power (r2= 0.45,r2= 0.71, respectively;P< 0.05). However, the attenuation in baroreflex sensitivity during heat stress appeared related to a shift in autonomic balance (shift in resting PI) rather than heat stress per se.
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DOI：
10.1113/jphysiol.1993.sp019541
发表时间：
1993
期刊：
The Journal of physiology
影响因子：
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发表时间：
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影响因子：
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DOI：
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发表时间：
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期刊：
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