Light-induced pigment aggregation in xanthophores of the medaka, Oryzias latipes.
Light-induced pigment aggregation in xanthophores of the medaka, Oryzias latipes.
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光诱导的青鳉、Oryzias latipes 黄色素中的色素聚集。
DOI：
10.1111/j.1600-0749.1998.tb00495.x
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
S. Kamagata
中科院分区：
文献类型：
--
作者：
N. Oshima;E. Nakata;M. Ohta;S. Kamagata
在细胞水平上研究了青鳉黄色素细胞对光的响应机制。受神经支配和去神经支配的成年青鳉的黄色素细胞在30秒内通过色素聚集对光（9,000勒克斯）作出反应，并且这种聚集不是通过细胞膜上的α-肾上腺素受体介导的。对光的最大敏感性在410-420 nm的波长处，并且光的直接效应是可逆的。黄色素细胞对光照的反应性夏季高于冬季。Ca 2+和钙调素不参与反应，但相反，cAMP和磷酸二酯酶（PDE）的重要作用被建议。对410-420 nm波长的光敏感的视色素的光感受似乎可能增加PDE活性，可能通过G蛋白，例如视网膜中的视细胞发生的，这导致细胞溶质cAMP水平降低，进而导致青鳉黄色素团内的色素聚集。
The response mechanism of medaka xanthophores to light was examined at the cellular level. Innervated and denervated xanthophores of adult medakas responded to light (9,000 lux) within 30 sec by pigment aggregation, and this aggregation was not mediated through alpha-adrenoceptors on the cell membrane. Maximum sensitivity to light was at wavelengths of 410-420 nm, and the direct effect of light was reversible. Xanthophore responsiveness to light in summer was higher than that in winter. Ca2+ and calmodulin were not involved in the response, but rather, an important role for cAMP and phosphodiesterase (PDE) was suggested. It seems likely that photoreception by visual pigment which is sensitive to light at wavelengths of 410-420 nm increases PDE activity, probably via a G-protein, such as occurs with visual cells in the retina, which causes a decrease in levels of cytosolic cAMP, in turn leading to pigment aggregation within medaka xanthophores.
DOI：
10.1016/s0021-9258(18)83166-0
发表时间：
1989-05
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
J P Y Kao;A. Harootunian;R. Tsien
通讯作者：
J P Y Kao;A. Harootunian;R. Tsien