Evening exposure to a light-emitting diodes (LED)-backlit computer screen affects circadian physiology and cognitive performance
Evening exposure to a light-emitting diodes (LED)-backlit computer screen affects circadian physiology and cognitive performance
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DOI：
10.1152/japplphysiol.00165.2011
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发表时间：
2011-05-01
影响因子：
3.3
通讯作者：
Stefani, Oliver
中科院分区：
文献类型：
--
作者：
Cajochen, Christian;Frey, Sylvia;Stefani, Oliver
2005年10月26日，李文辉.晚上暴露在发光二极管（LED）背光的电脑屏幕上会影响昼夜生理和认知能力。J Appl Physiol 110：1432-1438，2011.首次发表于2011年3月17日; doi：10.1152/japplphysiol.00165.2011。许多人花费越来越多的时间在配备有短波长（蓝色范围）的发光二极管（LED）的计算机屏幕前。因此，我们研究了在平衡交叉设计中，在受控实验室条件下对13名年轻男性志愿者的褪黑激素（生物钟的标志物）、警觉性和认知表现水平的影响。晚上暴露在白色LED背光屏幕下5小时，464 nm光发射量是其两倍多{辐照度为0，241瓦/（球面度X m（2））[W/（sr × m（2））]，2.1 × 10（13）光子/（cm（2）× s），在454和474 nm的波长范围内}比白色非LED背光屏幕[辐照度为0，099 W/（sr X m（2）），0.7 X 10（13）光子/（cm（2）X s），波长范围为454和474 nm]引起内源性褪黑激素和主观以及客观嗜睡的夜间上升的显著抑制，如通过在额叶脑区域中缓慢眼球运动和EEG低频活动（1-7 Hz）的发生率降低所指示的。同时，持续的注意力，确定的GO/NOGO任务;工作记忆/注意力，评估的“明确的时间”;和陈述性记忆表现在单词学习的范例中显着增强的LED背光屏幕相比，非LED条件。屏幕质量和视觉舒适度在两个屏幕条件中被评定为相同，而非LED屏幕倾向于被认为更明亮。我们的数据表明，计算机屏幕发出的光的光谱分布影响昼夜生理，警觉性和认知性能水平。挑战将是设计一个具有光谱轮廓的计算机屏幕，可以单独编程，以将定时的基本光信息添加到人类的昼夜节律系统中。
Cajochen C, Frey S, Anders D, Spati J, Bues M, Pross A, Mager R, Wirz-Justice A, Stefani O. Evening exposure to a light-emitting diodes (LED)-backlit computer screen affects circadian physiology and cognitive performance. J Appl Physiol 110: 1432-1438, 2011. First published March 17, 2011; doi: 10.1152/japplphysiol.00165.2011.-Many people spend an increasing amount of time in front of computer screens equipped with light-emitting diodes (LED) with a short wavelength (blue range). Thus we investigated the repercussions on melatonin (a marker of the circadian clock), alertness, and cognitive performance levels in 13 young male volunteers under controlled laboratory conditions in a balanced crossover design. A 5-h evening exposure to a white LED-backlit screen with more than twice as much 464 nm light emission {irradiance of 0,241 Watt/(steradian X m(2)) [W/(sr X m(2))], 2.1 X 10(13) photons/(cm(2) X s), in the wavelength range of 454 and 474 nm} than a white non-LED-backlit screen [ irradiance of 0,099 W/(sr X m(2)), 0.7 X 10(13) photons/(cm(2) X s), in the wavelength range of 454 and 474 nm] elicited a significant suppression of the evening rise in endogenous melatonin and subjective as well as objective sleepiness, as indexed by a reduced incidence of slow eye movements and EEG low-frequency activity (1-7 Hz) in frontal brain regions. Concomitantly, sustained attention, as determined by the GO/NOGO task; working memory/attention, as assessed by "explicit timing"; and declarative memory performance in a word-learning paradigm were significantly enhanced in the LED-backlit screen compared with the non-LED condition. Screen quality and visual comfort were rated the same in both screen conditions, whereas the non-LED screen tended to be considered brighter. Our data indicate that the spectral profile of light emitted by computer screens impacts on circadian physiology, alertness, and cognitive performance levels. The challenge will be to design a computer screen with a spectral profile that can be individually programmed to add timed, essential light information to the circadian system in humans.