Relationship of personality traits and drug of choice by cocaine addicts and heroin addicts

Relationship of personality traits and drug of choice by cocaine addicts and heroin addicts
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DOI:
10.1080/10826080701202726
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发表时间:
2008-01-01
影响因子:
2
通讯作者:
Ferri, M.
Ferri, M.
中科院分区:
医学4区
文献类型:
--
作者:
Gerra, G.;Bertacca, S.;Ferri, M.

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具体的人格特征和选择的单一精神药物之间的联系仍然不清楚,只是部分探讨。本研究比较了三组男性受试者:85例海洛因依赖患者(年龄:30.07 +/- 2.78),60例可卡因依赖患者(年龄:31.96 +/- 3.1),以及来自随机人群样本的50例健康受试者(年龄:33.25 +/- 1.45)。研究中纳入的患者表现出对海洛因或可卡因的长期依赖史,分别为5.2 +/- 2.5年、4.6 +/- 2.9年,并且在治疗中稳定,并且在诊断评估时戒断至少4周。海洛因依赖者(52.90%)正在接受美沙酮维持治疗。可卡因成瘾者(11.60%)使用选择性5-羟色胺再摄取抑制剂。人格特质采用明尼苏达多相人格问卷(MMPI-2)和克罗宁格三维人格问卷(TPQ)。攻击性的特征和量化是通过Buss-Durkee敌意量表(BDHI)来测量的。海洛因依赖者(A组)在MMPI的癔症、男女性和社会内向分量表上的得分显著高于可卡因成瘾者,而在TPQ的伤害回避(HA)分量表上的得分显著低于可卡因成瘾者。相比之下,分数的MMPI的hypopulia,精神病态偏差,偏执维度可卡因成瘾者比海洛因依赖患者更高。可卡因成瘾者在“直接”攻击性分量表和BDHI总分上的得分高于海洛因成瘾者。成瘾者在避免伤害(行为控制)方面与健康对照组没有差异。虽然可卡因成瘾者比海洛因成瘾者表现出更一致的精神病态偏差和公开的攻击性,但更高的伤害回避(行为控制),hypothelia(或担心自己的健康)和社会外向性可能会减少他们公开的反社会行为的倾向,并允许相对较高的社会融合水平。该研究的局限性被注意到。
The link between specific personality profiles and a single psychotropic drug of choice is still unclear and only partially explored. The present study compares three groups of male subjects: 85 patients manifesting heroin dependence (age: 30.07 +/- 2.78), 60 patients manifesting cocaine dependence (age: 31.96 +/- 3.1), and 50 healthy subjects from a random population sample (age: 33.25 +/- 1.45). The patients included in the study showed a long-lasting history of dependence on heroin or cocaine, respectively, 5.2 +/- 2.5 years, 4.6 +/- 2.9 years, and were stabilized in treatment, and abstinent, at least 4 weeks at the time of the diagnostic assessment. Heroin addicts (52.90%) were on methadone maintenance treatment. Cocaine addicts (11.60%) were treated with selective serotonin reuptake inhibitors. Personality traits were measured by the Minnesota Multiphasic Personality Inventory (MMPI-2) and Cloninger's Three-dimensional Personality Questionnaire (TPQ). Character and quantification of aggressiveness were measured by the Buss-Durkee Hostility Inventory (BDHI). Heroin-dependent patients (group A) scored significantly higher on hysteria, masculine-feminine and social introversion subscales of the MMPI, and significantly lower on the harm avoidance (HA) subscale of the TPQ than cocaine addicts. In contrast, scores on the MMPI for hypochondria, psychopathic deviance, and paranoia dimensions were more elevated in cocaine addicts than in heroin-dependent patients. Cocaine addicts scored higher than heroin addicts on the "direct" aggressiveness subscale and on the BDHI total score. Cocaine addicts did not differ from healthy controls on harm avoidance (behavioral control). Although cocaine addicts showed more consistent psychopathic deviance and overt aggressiveness than heroin addicts, higher harm avoidance (behavioral control), hypochondria (or worry about their health), and social extroversion may reduce their proneness to overt antisocial behavior and allow relatively higher levels of social integration. The study's limitations are noted.