THE METABOLISM OF FATTY ACIDS IN THE RAT. VI. ARACHIDONIC ACID.
THE METABOLISM OF FATTY ACIDS IN THE RAT. VI. ARACHIDONIC ACID.
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大鼠体内脂肪酸的代谢。
DOI：
10.1111/j.1748-1716.1965.tb04148.x
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发表时间：
1965
期刊：
影响因子：
--
通讯作者：
G. Göransson
中科院分区：
文献类型：
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作者：
G. Göransson
Goransson，G.大鼠脂肪酸的代谢。六.花生四烯酸。《生理学学报》，1965年。64. 1-5.同时给雄性大鼠注射-H3标记的花生四烯酸和C14标记的棕榈酸。花生四烯酸优先纳入肝磷脂，这可能是预期的优势，这种脂肪酸在肝磷脂相比，甘油酯。最初，标记的花生四烯酸和标记的棕榈酸以相似的速率被氧化，但在稍后的时间，从整个动物中回收的花生四烯酸比棕榈酸多。这可能是由于花生四烯酸优先掺入磷脂，同时磷脂的周转率低，特别是含有必需脂肪酸的磷脂。血液甘油酯中的标记模式与相应肝脏组分中的标记模式非常相似。
Goransson, G. The metabolism of fatty acids in the rat. VI. Arachidonic acid. Acta physiol. scand. 1965. 64. 1–5. -H3-labeled arachidonic acid and C14-labeled palmitic acid were simultaneously injected into male rats. Arachidonic acid was preferentially incorporated into liver phospholipids as might be expected from the preponderance of this fatty acid in liver phospholipids as compared to glycerides. Initially, the labeled arachidonic acid and the labeled palmitic acid were oxidized at similar rates but at later times more arachidonic acid than palmitic acid was recovered from the whole animal. This may be explained by the preferential incorporation of arachidonic acid into phospholipid in combination with the low turnover rate of the phospholipids, especially those containing essential fatty acids. The pattern of label in the blood glycerides closely resembled that in the corresponding liver fraction.