Biological Safety of Mixed Acid Heat Treatment in SLM (Selective Laser Melting Technique) Titanium Mesh
Biological Safety of Mixed Acid Heat Treatment in SLM (Selective Laser Melting Technique) Titanium Mesh
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SLM（选择性激光熔化技术）钛网混合酸热处理的生物安全性
DOI：
10.11223/jarde.16.27
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
and Takaaki UENO
中科院分区：
文献类型：
--
作者：
Shihoko INUI;Kayoko YAMAMOTO;Nahoko KATO-KOGOE;Yoichiro NAKAJIMA;Kazuya INOUE;Hiroyuki NAKANO;Seiji YAMAGUCHI;Azumi HIRATA;Yoichi KONDO;and Takaaki UENO
采用选择性激光熔化(SLM)技术对钛网片进行混酸加热表面改性，并将其应用于大鼠颅骨骨缺损模型。通过宏观和微观观察炎症反应来评价表面混酸热处理的安全性。术后2、4、7周SLM钛网组未见炎性反应加重。这些结果表明，混酸和热处理表面改性钛网是安全的。
A titanium (Ti) mesh using the Selective Laser Melting (SLM) technique was subjected to surface modification by mixed acid heating, and it was applied to a rat calvarial bone defect model. Safety of the mixed acid heat treatment on the surface was evaluated by investigating the inflammatory response based on macroscopic and microscopic findings. Worsening of inflammatory reactions was not observed in the SLM Ti mesh-embedded group at 2, 4 or 7 weeks. These results suggest that mixed acid and heat treatment surface modification Ti mesh is safe.