Symmetry in Infancy: Analysis of Motor Development in Autism Spectrum Disorders
Symmetry in Infancy: Analysis of Motor Development in Autism Spectrum Disorders
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DOI：
10.3390/sym1020215
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发表时间：
2009-12-01
期刊：
影响因子：
2.7
通讯作者：
Venuti, Paola
中科院分区：
文献类型：
--
作者：
Esposito, Gianluca;Venuti, Paola
运动不对称，定义为运动或姿势缺乏对称性，通常在许多发育正常的儿童中短暂观察到。然而，如果这种不对称持续存在，则可能是神经系统疾病的迹象。最近的研究表明，运动不对称可能是自闭症谱系障碍（ASD）的早期症状。ASD涉及一系列不同程度的社会、认知和行为问题，被认为是多种病因机制的最终共同途径。此外，ASD的早期识别已被认为是治疗的关键方面。我们的研究旨在分析ASD婴儿与典型发育婴儿（TD）或其他发育迟缓（DD）婴儿在出生后第一年的运动里程碑的对称性。我们的研究结果强调，有不同的模式的电机对称的群体。特别是，患有ASD的婴儿得分明显低于TD和DD婴儿（不对称程度较高）。我们还确定了两个ASD婴儿亚组，一个具有典型水平，另一个具有较低水平的运动功能。的诊断和治疗的研究的意义进行了说明。
Motor asymmetry, defined as the lack of symmetry in movements or postures, is often observed briefly in many typically developing children. However, if such asymmetry persists, it may be a sign of neurological disease. Recent studies have suggested that motor asymmetries may be an early symptom of Autism Spectrum Disorders (ASD). ASD involve a range of social, cognitive, and behavioral problems, at different degrees of functioning, which are thought to be the final common pathway of multiple etiological mechanisms. Furthermore, early identification of ASD has been recognized as a critical aspect for treatment. Our study aims to analyze symmetry in the motor milestones of infants with ASD compared with typically developing infants (TD) or infants with other developmental delay (DD) during the first year of life. Our results highlight that there are different patterns of motor symmetry in the groups. In particular, infants with ASD scored significantly poorer (higher levels of asymmetry) then the TD and DD infants. We also identified two subgroups of infants with ASD, one with a typical level and the other with a lower level of motor functioning. Implications of the study for diagnosis and treatment are described.