Comparison of human and chimpanzee zeta 1 globin genes.
Comparison of human and chimpanzee zeta 1 globin genes.
复制标题
人类和黑猩猩 zeta 1 珠蛋白基因的比较。
DOI:
10.1007/bf02115686
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发表时间:
1985
影响因子:
3.9
通讯作者:
Schmid,CW
中科院分区:
文献类型:
--
作者:
Willard,C;Wong,E;Hess,JF;Shen,CK;Chapman,B;Wilson,AC;Schmid,CW
The DNA base sequences of the entire chimpanzee ξ1 globin gene and an additional 1 kb of DNA flanking both the human and chimpanzee genes have been determined. Whereas the human ξ1 gene contains a termination codon in the sixth position, the chimpanzee gene appears to be functional. This finding confirms Proudfoot et al.'s suggestion that the human ξ1 gene was recently inactivated. Like the corresponding human ξ1 and ξ2 genes, the first and second introns of the chimpanzee ξ1 gene are occupied largely by tandem repeats of short oligonucleotides. These tandem repeats have undergone several rearrangements since the divergence of the human and chimpanzee ξ1 genes.