The effect of life course socioeconomic position on crystallised cognitive ability in two large UK cohort studies: a structured modelling approach.
The effect of life course socioeconomic position on crystallised cognitive ability in two large UK cohort studies: a structured modelling approach.
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DOI：
10.1136/bmjopen-2016-014461
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发表时间：
2017-06-02
期刊：
影响因子：
2.9
通讯作者：
Hardy R
中科院分区：
文献类型：
--
作者：
Landy R;Head J;Richards M;Hardy R
本研究系统比较了积累、敏感期、关键期和社会流动等与生命历程社会经济地位（SEP）和成人结晶认知能力相关的模型，这些模型尚未得到全面的研究。两项前瞻性队列研究。医学研究委员会全国健康与发展调查（NSHD）出生队列研究的5,362名参与者和白厅II职业队列研究的10,308名参与者。童年SEP采用父亲职业SEP，成年早期SEP采用学历SEP，成人SEP采用自身职业SEP，各生命历程模型采用饱和模型进行比较。使用多重归因来解释缺失的数据，敏感期模型包含不同系数的童年、成年早期和成年SEP项，对NSHD和Whitehall II队列中的男性和女性都提供了最佳的拟合。成年早期SEP在NSHD女性中具有最大的系数，而对于NSHD男性，成年早期和成年SEP具有相似的系数。在白厅II中，成人SEP对男性和女性都有最大的效应量。在两个队列中，所有三个时间段的敏感期都是最适合成人结晶认知能力的生命历程模型，包括儿童SEP的影响。直接比较生命历程模型以确定哪一个是最合适的是很重要的。
This study systematically compared accumulation, sensitive period, critical period and social mobility models relating life course socioeconomic position (SEP) and adult crystallised cognitive ability, which has not been comprehensively investigated. Two prospective cohort studies. Five thousand three hundred and sixty-two participants in the Medical Research Council National Survey of Health and Development (NSHD) Birth Cohort Study and 10 308 participants in the Whitehall II Occupational Cohort Study. Childhood SEP was measured by father’s occupational SEP, early adulthood SEP by educational qualifications and adult SEP by own occupational SEP. Each life course model was compared with a saturated model. Using multiple imputation to account for missing data, the sensitive period model, which contained childhood, early adulthood and adult SEP terms, with different coefficients, provided the best fit for both men and women in the NSHD and Whitehall II cohorts. Early adulthood SEP had the largest coefficient in NSHD women, whereas for NSHD men early adulthood and adult SEP had similar coefficients. In Whitehall II adult SEP had the largest effect size for both men and women. Sensitive period with all three time periods was the most appropriate life course models for adult crystallised cognitive ability in both cohorts, including an effect of childhood SEP. It is important to directly compare the life course models to determine which is the most appropriate.
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影响因子：
13.6
作者：
Gallacher, JEJ;Elwood, PC;Huppert, FA
通讯作者：
Huppert, FA
影响因子：
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作者：
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通讯作者：
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DOI：
10.1093/geronb/62.6.s404
发表时间：
2007-11-01
影响因子：
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DOI：
10.1093/geronb/60.2.s93
发表时间：
2005-03-01
影响因子：
6.2
作者：
Luo, Y;Waite, LJ
通讯作者：
Waite, LJ