Parkinson's disease among American Indians and Alaska natives: A nationwide prevalence study
Parkinson's disease among American Indians and Alaska natives: A nationwide prevalence study
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DOI：
10.1002/mds.25153
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发表时间：
2012-09-01
影响因子：
8.6
通讯作者：
Cheek, James E.
中科院分区：
文献类型：
--
作者：
Gordon, Paul H.;Mehal, Jason M.;Cheek, James E.
背景资料：本研究的目的是确定帕金森病（PD）的患病率在美洲印第安人和阿拉斯加原住民（AI/AN）的人。方法：我们分析了2002年至2009年期间AI/AN患者的记录，使用印度卫生服务局的住院和门诊就诊数据。粗患病率和年龄调整患病率，使用2000年预测的美国人口作为标准，确定总体和年龄组，性别，时期和地区。结果：估计有2613名AI/AN患者诊断为PD（粗患病率，143.8/100，000）。患病率随着年龄的增长而增加，直到84岁。年龄调整后的患病率为355.7，男性高于女性（P <0.0001）。各地区的发病率不同（P < .0001）。结论：帕金森病在AI/AN人群中普遍存在。流行率随年龄增长而增加，因地理区域而异，男性高于女性。需要以社区为基础的研究来确定发病率，检查风险因素，并确定AI/AN人群中PD的性别和区域差异的原因。(c)2012运动障碍协会
Background: The objective of this study was to determine the prevalence of Parkinson's disease (PD) among American Indian and Alaska Native (AI/AN) people. Methods: We analyzed records for AI/AN people between 2002 and 2009 using inpatient and outpatient visit data from the Indian Health Service. Crude and age-adjusted prevalence, using the 2000 projected US population as the standard, was determined overall and by age group, sex, period, and region. Results: An estimated 2613 AI/AN people carried the diagnosis of PD (crude prevalence, 143.8/100,000). Prevalence increased with age through 84 years. The age-adjusted rate was 355.7 and was higher among men than women (P < .0001). Rates differed by region (P < .0001). Conclusions: Parkinson's disease is prevalent among AI/AN people. The prevalence increases with age, varies by geographic region, and is higher among men than women. Community-based studies are needed to define incidence, examine risk factors, and determine reasons for sex and regional differences in PD among AI/AN people. (c) 2012 Movement Disorder Society