Concerning the form of biochemically active vanadium
Concerning the form of biochemically active vanadium
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关于生化活性钒的形态
DOI：
10.1098/rspb.1981.0025
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
I. Glynn
中科院分区：
文献类型：
--
作者：
K. Rubinson;I. Glynn
概述了钒的描述化学，因为它与生理环境有关。考虑到钒浓度、pH、配位配体和螯合物、其他阳离子的存在、氧化还原电位和各种含钒物质的动力学，提出以下建议。游离钒离子将是单体的。单体钒（V）和钒（IV）将各自以特定的水合形式存在。细胞外的钒将以钒酸盐Vv形式存在。细胞内的钒很可能主要以氧钒（VIV）形式存在。细胞外钒（V）和细胞内钒（IV）都将结合到二齿或三齿配体（如果有的话）。如果涉及钒的氧化还原过程相对于跨膜转运是快速的，则跨膜电位将不与VV / V IV能斯特电位耦合。
A survey has been made of the descriptive chemistry of vanadium as it pertains to physiological environments. Taking into account the vanadium concentration, pH, coordinating ligands and chelates, presence of other cations, oxidation-reduction potentials and the kinetics of the various vanadium-containing species, the following suggestions are made. Free vanadium ions will be monomeric. Monomeric vanadium(V) and vanadium(IV) will each exist in a specific hydrated form. Extracellular vanadium will be in the vanadate, Vv, form. Intracellular vanadium will most likely be predominately in the vanadyl, VIV, form. Both extracellular vanadium(V) and intracellular vanadium(IV) will be bound to bi- or tridentate ligands if at all. If oxidation-reduction processes involving vanadium are fast relative to transmembrane transport, the transmembrane potential will not be coupled to the VV / V IV Nernstian potential.